4 documents found, page 1 of 1
Real-world effectiveness of aromatase inhibitors and fulvestrant in HR+/HER2- a...
Teodoro, Maria Inês; Mayer, Alexandra; Miranda, Ana da Costa; Nunes, Hugo; Costa, Filipa Alves da; Lourenço, AntónioBackground: Monotherapy with aromatase inhibitors and fulvestrant were the standard-of-care for hormone receptor-positive (HR+)/human epidermal growth factor receptor-type2 negative (HER2-) advanced breast cancer, before integration of cyclin-dependent kinase 4/6 inhibitors. Effectiveness data is essential for regulatory action, but little is known about real-world use of aromatase inhibitors and fulvestrant. M...
Effectiveness of palbociclib with aromatase inhibitors for the treatment of adv...
Costa, Filipa Alves da; Borges, Fábio Cardoso; Ramos, Adriana; Mayer, Alexandra; Brito, Claudia; Ramos, Catarina; Bernardo, Catarina; Cossito, MarianeBackground: New drugs for locally advanced or metastatic breast cancer have led to clinical benefits, aside with increasing costs to healthcare systems. The current financing model for health technology assessment (HTA) privileges real-world data. As part of the ongoing HTA, this study aimed to evaluate the effectiveness of palbociclib with aromatase inhibitors (AI) and compare it with the efficacy reported in ...
The Portuguese Version of the European Deprivation Index: An Instrument to Stud...
Ribeiro, Ana Isabel; Mayer, Alexandra; Miranda, Ana; de Pina, Maria de FátimaIntroduction: Tackling socioeconomic health inequalities is a big public health challenge and ecological deprivation indexes are essential instruments to monitor and understand them. In Portugal, no standard ecological deprivation index exists, contrasting with other countries. We aimed to describe the construction of the Portuguese version of a transnational deprivation index, European Deprivation Index.Materi...
Breast Cancer Patients Survival and Associated Factors: Reported Outcomes from ...
André, Maria do Rosario; Amaral, Sandra; Mayer, Alexandra; Miranda, Ana; ROR SUL, Working GroupObjectives: Although the breast cancer incidence in Portugal is lower than the European average, it is the most frequent cancer in women. Overall, mortality rates are heterogeneous throughout Portugal. Implicated factors may include demographic and socioeconomic aspects, tumor biological characteristics, and access to medical care. The aim of this study is to detect survival differences in female breast cancer ...