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The conserved and divergent roles of carbonic anhydrases in the filamentous fun...

Han, Kap-Hoon; Chun, Yoon-Hee; Figueiredo, Bárbara de Castro Pimentel; Soriani, Frederico Marianetti; Savoldi, Marcela; Almeida, Agostinho João Ramalho

Carbon dioxide (CO(2)) and its hydration product bicarbonate (HCO(3)(-)) are essential molecules in various physiological processes of all living organisms. The reversible interconversion between CO(2) and HCO(3)(-) is in equilibrium. This reaction is slow without catalyst, but can be rapidly facilitated by Zn(2+)-metalloenzymes named carbonic anhydrases (CAs). To gain an insight into the function of multiple c...


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