Multiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...
Publisher Copyright: © 2025 by the authors.; Multiple myeloma is a clonal plasma cell malignancy with a highly variable range of clinical manifestations. Over recent decades, substantial progress has been made in laboratory diagnostics, which has deepened our understanding of disease biology, improved risk stratification, and informed treatment strategies. In an era of transformation and innovation, conventiona...
Publisher Copyright: © 2024 Portuguese Society of Pediatrics.; The Portuguese Neonatal Society updates the growth charts recommended for term and preterm infants. The suitability of the growth chart depends on the gestational age, the purpose of the measurement, and the life cycle stage. To classify intrauterine growth at birth, the Fenton 2013 growth charts, which are based on anthropometric records at birth, ...
The growth charts and reference values for preterm infants are revisited and recommendations for their use are updated by the Portuguese Neonatal Society. To assess intrauterine growth: The cross-sectional sex specific Fenton 2013 charts, based on birth weight, length, and head circumference, are the most appropriate. Neonates born with weight < 3rd percentile are classified as small-for-gestational-age and tho...