1 document found, page 1 of 1

Accessing new 5-α-(3,3-Disubstituted Oxindole)-Benzylamine Derivatives from Isa...

A one-step, three-component Petasis reaction of isatin derived 5-arylboronate-3-substituted oxindole derivatives with salicylaldehydes and secondary amines affords new enantiomerically pure structurally diverse 5-alpha-(3-substituted-oxindole)-benzylamine derivatives. The reaction shows good substrate and reagent scope affording the products with good to excellent yields (up to >99 % yield) and enantioselectivi...