2 documents found, page 1 of 1
Isoquinolinequinone N-oxides as potent antitumor compounds against pancreatic c...
Rodrigues, Rúben; Kruschel, Ryan D.; McCarthy, Florence O.; Vasconcelos, M. Helena; P. R. Xavier, CristinaBackground: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies, being the 7th leading cause of cancer-related mortality worldwide. PDAC remains associated with an extremely poor prognosis, owing to drug resistance and to the lack of alternative therapeutic options. Standard chemotherapy typically involves gemcitabine, either alone or combined with paclitaxel. Moreover, Chitinase-...
29th Annual GP2A Medicinal Chemistry Conference
Helesbeux, Jean-Jacques; Carro, Laura; McCarthy, Florence O.; Moreira, Vânia M.; Giuntini, Francesca; O'Boyle, Niamh; Matthews, Susan E.The 29th Annual GP2A (Group for the Promotion of Pharmaceutical chemistry in Academia) Conference was a virtual event this year due to the COVID-19 pandemic and spanned three days from Wednesday 25 to Friday 27 August 2021. The meeting brought together an international delegation of researchers with interests in medicinal chemistry and interfacing disciplines. Abstracts of keynote lectures given by the 10 invit...