6 documents found, page 1 of 1
Genome diversity, recombination, and virulence across the major lineages of Par...
Muñoz, José F.; Farrer, Rhys A.; Desjardins, Christopher A.; Gallo, Juan E.; Sykes, Sean; Sakthikumar, Sharadha; Misas, Elizabeth; Whiston, Emily A.Made available in DSpace on 2022-04-29T23:53:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-09-01; National Institute of Allergy and Infectious Diseases; The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic to Latin America. To examine the genome evolution and the diversity of Para...
Down-regulation of TUFM impairs host cell interaction and virulence by Paracocc...
Marcos, Caroline Maria [UNESP]; Tamer, Gabrielle [UNESP]; de Oliveira, Haroldo Cesar [UNESP]; Assato, Patricia Akemi [UNESP]; Scorzoni, Liliana [UNESP]Made available in DSpace on 2020-12-12T01:46:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The genus Paracoccidioides consist of dimorphic fungi geographically limited to the subtropical regions of Latin America, which are responsible for causing deep systemic mycosis in humans. However, the molecular mechanisms by which Paracocci...
Genome Diversity, Recombination, and Virulence across the Major Lineages of Par...
Munoz, Jose F.; Farrer, Rhys A.; Desjardins, Christopher A.; Gallo, Juan E.; Sykes, Sean; Sakthikumar, Sharadha; Misas, Elizabeth; Whiston, Emily A.Made available in DSpace on 2018-11-28T03:37:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-09-01; Colciencias; HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID); Wellcome Trust; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause paracoccidioidomycosis, a neglected health...
Decreased expression of 14-3-3 in Paracoccidioides brasiliensis confirms its in...
Marcos, Caroline Maria [UNESP]; da Silva, Julhiany de Fátima [UNESP]; de Oliveira, Haroldo Cesar [UNESP]; Assato, Patrícia Akemi [UNESP]Made available in DSpace on 2018-12-11T17:27:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-02-17; The interaction between the fungal pathogen Paracoccidioides brasiliensis and host cells is usually mediated by specific binding events between adhesins on the fungal surface and receptors on the host extracellular matrix or cell surface. One molecule implicated in the P. brasiliensis-host interaction i...
Hemoglobin Uptake by Paracoccidioides spp. Is Receptor-Mediated
Bailão, Elisa Flávia Luiz Cardoso; Parente, Juliana Alves; Pigosso, Laurine Lacerda; Castro, Kelly Pacheco de; Fonseca, Fernanda LopesIron is essential for the proliferation of fungal pathogens during infection. The availability of iron is limited due to its association with host proteins. Fungal pathogens have evolved different mechanisms to acquire iron from host; however, little is known regarding how Paracoccidioides species incorporate and metabolize this ion. In this work, host iron sources that are used by Paracoccidioides spp. were in...
Comparative genomic analysis of human fungal pathogens causing paracoccidioidom...
Desjardins, Christopher A.; Champion, Mia D.; Holder, Jason W.; Muszewska, Anna; Goldberg, Jonathan; Bailão, Alexandre Melo; Brígido, Marcelo de MacedoParacoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, is coupled with a thermally regulated transition from a soil-dwelling filamentous form to a yeast-like pathogenic form. To better understand the genetic basis of growth and pathogenicity in ...