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Food addiction: prevalence, psychopathological correlates and associations with...

Nunes-Neto, Paulo R.; Köhler, Cristiano A.; Schuch, Felipe B.; Solmi, Marco; Quevedo, João; Maes, Michael; Murru, Andrea; Vieta, Eduard

Objective: To determine the prevalence of food addiction in a large Brazilian non-clinical sample. Sociodemographic and psychopathological correlates of food addiction as well as associations with quality (QoL) domains were also investigated. Methods: This cross-sectional study obtained data from a Brazilian anonymous web-based research platform (N = 7639; 71.3% females). Participants provided sociodemographic ...

Date: 2018   |   Origin: Oasisbr

Gut microbiota, bacterial translocation, and interactions with diet : pathophys...

Slyepchenko, Anastasiya; Maes, Michael; Jacka, Felice N.; Köhler, Cristiano A.; Barichello, Tatiana; McIntyre, Roger S.; Berk, Michael; Grande, Iria

Background: Persistent low-grade immune-inflammatory processes, oxidative and nitrosative stress (O&NS), and hy- pothalamic-pituitary-adrenal axis activation are integral to the pathophysiology of major depressive disorder (MDD). The microbiome, intestinal compositional changes, and re-sultant bacterial translocation add a new element to the bi- directional interactions of the gut-brain axis; new evidence impli...

Date: 2017   |   Origin: Oasisbr

Screening for bipolar spectrum disorders : a comprehensive meta-analysis of acc...

Carvalho, André F.; Takwoingi, Yemisi; Sales, Paulo Marcelo G.; Soczynska, Joanna K.; Köhler, Cristiano A.; Freitas, Thiago H.; Quevedo, João

Background: Bipolar spectrum disorders are frequently under-recognized and/or misdiagnosed in various settings. Several in fl uential publications recommend the routine screening of bipolar disorder. A systematic review and meta-analysis of accuracy studies for the bipolar spectrum diagnostic scale (BSDS), the hypomania checklist (HCL-32) and the mood disorder questionnaire (MDQ) were performed. Methods: The Pu...

Date: 2017   |   Origin: Oasisbr

Prevention and reversal of ketamine-induced schizophrenia related behavior by m...

Monte, Aline Santos; Souza, Greicy Coelho de; McIntyre, Roger S.; Soczynska, Joanna K.; Santos, Júnia Vieira dos; Cordeiro, Rafaela Carneiro

It has been hypothesized that oxidative imbalance and alterations in nitrergic signaling play a role in the neurobiology of schizophrenia. Preliminary evidence suggests that adjunctive minocycline treatment is efficacious for cognitive and negative symptoms of schizophrenia. This study investigated the effects of minocycline in the prevention and reversal of ketamine-induced schizophrenia-like behaviors in mice...

Date: 2014   |   Origin: Oasisbr

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