1 document found, page 1 of 1

Sort by Issue Date
go first page go previous page
go to page: 1
go next page go last page
rss feed search results

Inhalation of the prodrug PI3K inhibitor CL27cimproves lung function in asthma ...

Campa, Carlo C.; Silva, Rangel L.; Margaria, Jean P.; Piral, Tracey; Mattos, Matheus S.; Kraemer, Lucas R.; Reis, Diego C.; Grosa, Giorgio

PI3K activation plays a central role in the development of pulmonary inflammation and tissue remodeling. PI3K inhibitors may thus offer an improved therapeutic opportunity to treat non-resolving lung inflammation but their action is limited by unwanted on-target systemic toxicity. Here we present CL27c, a prodrug pan-PI3K inhibitor designed for local therapy, and investigate whether inhaled CL27c is effective i...

Date: 2019   |   Origin: Oasisbr
More info.
go first page go previous page
go to page: 1
go next page go last page
rss feed search results

1 Results

Queried text

Refine Results

Author





















Date


Document Type


Access rights


Resource


Subject