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Anti-inflammatory effect of a sulphated polysaccharide fraction extracted from ...

Brito, Tarcisio Vieira de; Prudêncio, Rafael da Silva; Sales, Adriano Bezerra; Vieira Júnior, Francisco das Chagas; Candeira, Starley Jone Nogueira

Objectives The aim of this study was to evaluate the anti-inflammatory effect of a sulphated polysaccharide fraction (PLS) extracted from the alga Hypnea musciformis and investigate the possible involvement of the nitric oxide (NO) pathway in this effect. Methods The anti-inflammatory activity of PLS was evaluated using inflammatory agents (carrageenan and dextran) to induce paw oedema and peritonitis in Swiss ...

Date: 2014   |   Origin: Oasisbr

Avaliação do efeito gastroprotetor do Sildenafil (Viagra®) na lesão gástrica in...

Medeiros, Jand-Venes Rolim

Recently, we demonstrated that sildenafil has protective effects against NSAID- induced gastric damage in rats, by a decrease in leukocytes adherence and increase in gastric blood flow (Santos CL et al, BJP, 2005). Ethanol induced gastric hemorrhagic damage in rats, by an increase in free radical production and decrease in mucosal glutathione concentration. AIMS: Aim of was work is to investigate if sildenafil ...

Date: 2012   |   Origin: Oasisbr

Efeitos gastroprotetor e procinético do sulfeto de hidrogênio (H2S) em camundon...

Medeiros, Jand-Venes Rolim

Recently, the involvement of H2S has been demonstrated in several physiological and pathological conditions, being constitutively produced in mammalian tissues. AIM: To study the role of H2S on both the gastric mucosa defense and the control of gastric motility in mice, and additionally to evaluate the participation of KATP channels, capsaicin-sensitive afferent neurons and TRPV1 receptors in these effects. MET...

Date: 2012   |   Origin: Oasisbr

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