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Enteropathogenic Escherichia coli Infection Induces Diarrhea, Intestinal Damage...

Ledwaba, Solanka E.; Costa, Deiziane V. S.; Bolick, David T.; Giallourou, Natasa; Medeiros, Pedro H. Q. S.; Swann, Jonathan R.; Traore, Afsatou N.

Enteropathogenic E. coli (EPEC) are recognized as one of the leading bacterial causes of infantile diarrhea worldwide. Weaned C57BL/6 mice pretreated with antibiotics were challenged orally with wild-type EPEC or escN mutant (lacking type 3 secretion system) to determine colonization, inflammatory responses and clinical outcomes during infection. Antibiotic disruption of intestinal microbiota enabled efficient ...

Date: 2021   |   Origin: Oasisbr

Etiology and severity of diarrheal diseases in infants at the semiarid region o...

Lima, Aldo A. M.; Oliveira, Domingos B.; Quetz, Josiane S.; Havt, Alexandre; Prata, Mara M. G.; Lima, Ila F. N.; Soares, Alberto M.; Q. Filho, José

Background Diarrheal diseases are an important cause of morbidity and mortality among children in developing countries. We aimed to study the etiology and severity of diarrhea in children living in the low-income semiarid region of Brazil. Methodology This is a cross-sectional, age-matched case-control study of diarrhea in children aged 2–36 months from six cities in Brazil’s semiarid region. Clinical, epidemio...

Date: 2019   |   Origin: Oasisbr

Epidemiology of enteroaggregative Escherichia coli infections and associated ou...

Rogawski, Elizabeth T.; Guerrant, Richard L.; Havt, Alexandre; Lima, Ila F. N.; Medeiros, Pedro H. Q. S.; Seidman, Jessica C.; McCormick, Benjamin J. J.

Background Enteroaggregative E. coli (EAEC) have been associated with mildly inflammatory diarrhea in outbreaks and in travelers and have been increasingly recognized as enteric pathogens in young children with and without overt diarrhea. We examined the risk factors for EAEC infections and their associations with environmental enteropathy biomarkers and growth outcomes over the first two years of life in eight...

Date: 2017   |   Origin: Oasisbr

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