4 documents found, page 1 of 1
Antigens of Coccidioides posadasii as an Important Tool for the Immunodiagnosis...
Medrano, Delia Jessica Astete; Cordeiro, Rossana de Aguiar; Patoilo, Kharla Rabelo Nobre; Praciano, Silviane BandeiraSerologic diagnosis has been presented as a safe alternative for coccidioidomycosis. However, commercial kits based on coccidioidal antibodies available in the USA are considered too expensive for laboratories outside that country. In this study, we describe the preparation of antigens for detection of human coccidioidal antibodies by the immunodiffusion test (ID) and enzyme immunoassay (EIA). Antigens were tes...
Cotrimoxazole enhances the in vitro susceptibility of Coccidioides posadasii to...
Medrano, Delia Jessica Astete; Cordeiro, Rossana de Aguiar; Marques, Francisca Jakelyne de Farias; Andrade, Heuziwanne Tavares LeiteThe aim of the present study was to evaluate the effect of cotrimoxazole on the in vitro susceptibility of Coccidioides posadasii strains to antifungals. A total of 18 strains of C. posadasii isolated in Brazil were evaluated in this study. The assays were performed in accordance with the Clinical and Laboratory Standards Institute guidelines and the combinations were tested using the checkerboard method. The m...
In vitro synergistic effects of antituberculous drugs plus antifungals against ...
Cordeiro, Rossana de Aguiar; Brilhante, Raimunda Sâmia Nogueira; Rocha, Marcos Fábio Gadelha; Medrano, Delia Jessica Astete; Monteiro, André JallesThe aim of the present study was to evaluate the in vitro interactions of antituberculous drugs (ATDs) withantifungalsagainst Coccidioidesposadasii .Eighteendrugcombinations,formedbyanATD(isoniazid, pyrazinamideorethambutol)plusanantifungal(amphotericinB,ketoconazole,itraconazole,fluconazole, voriconazole or caspofungin), were tested using the checkerboard method. All the antimicrobial combi- nations inhibited ...
Candidemia em hospital terciário brasileiro: a importância da Candida parapsilosis
Medrano, Delia Jessica Astete; Brilhante, Raimunda Sâmia Nogueira; Cordeiro, Rossana de Aguiar; Rocha, Marcos Fábio GadelhaThe aim of this study was to perform a retrospective analysis of cases of candidemia in a Brazilian hospital in the city of Fortaleza, Ceará. A total of 50 blood cultures were analyzed from 40 candidemic patients. The mycological diagnosis was based on the phenotypical analysis and the patients' data were recorded in appropriate files. The most frequent species were Candida parapsilosis (n = 18), followed by C....