6 documents found, page 1 of 1
Electroactive polymer-based materials as a novel approach for cardiac tissue en...
Meira, Rafaela MarquesMost current scaffolds for cardiac tissue engineering (TE) lack electroactive responses and possess inadequate mechanical properties, hindering their effectiveness in promoting cardiac regeneration and restoring function after injury. These limitations arise from their inability to replicate the heart’s electromechanical nature. Electroactive materials, particularly piezoelectric polymers, offer a promising app...
Biodegradable and biocompatible collagen-based hybrid materials for force sensi...
Andonegi, Mireia; Meira, Rafaela Marques; Correia, Daniela M.; Pereira, Nelson Miguel Macedo Silva; Costa, Carlos Miguel Silva; Lanceros-Mendez, S.With the aim of replacing synthetic macromolecules by biological macromolecules for advanced applications, collagen films were produced with two different ionic liquids (ILs), choline dihydrogen phosphate ([Ch][DHP]) and choline serinate ([Ch][Seri]), added in order to modulate the electrical responses. The films were prepared by casting, varying IL content between 0 and 6 wt%. The morphology and thermal proper...
Electrospun magnetic ionic liquid based electroactive materials for tissue engi...
Fernandes, Liliana C.; Meira, Rafaela Marques; Correia, Daniela Maria Silva; Ribeiro, Clarisse Marta Oliveira; Fernandez, Eduardo; Tubio, Carmen R.Functional electrospun fibers incorporating ionic liquids (ILs) present a novel approach in the development of active microenviroments due to their ability to respond to external magnetic fields without the addition of magnetic particles. In this context, this work reports on the development of magnetically responsive magneto-ionic fibers based on the electroactive polymer poly(vinylidene fluoride) and the magn...
Ionic liquid-based electroactive materials: a novel approach for cardiac tissue...
Meira, Rafaela Marques; Correia, Daniela Maria Silva; García Díez, A.; Lanceros-Méndez, S.; Ribeiro, C.Cardiac tissue regeneration strategies are increasingly taking advantage of electroactive scaffolds to actively recreate tissue microenvironment. In this context, this work reports on advanced materials based on two different ionic liquids (ILs), 2- hydroxyethyl-trimethylammonium dihydrogen phosphate ([Ch][DHP]) and choline bis(trifluoromethylsulfonyl)imide ([Ch][TFSI]), combined with poly(vinylidene fluoride-c...
Poly(lactic-co-glycolide) based biodegradable electrically and magnetically act...
Hermenegildo, B.; Meira, Rafaela Marques; Correia, Daniela Maria Silva; Díez, A. G.; Ribeiro, Sylvie Oliveira; Serra, J. P.; Ribeiro C.Polymer scaffolds are playing an increasing role in tissue engineering (TE), although there is still a need to improve their biomimicry of cellular microenvironments, by having smart scaffolds with an active response, which can improve tissue regeneration. This work reports on the novel combination of poly(lactic-co-glycolide) (PLGA) with the ionic liquid (IL) choline bis(trifluoromethylsulfonyl)imide ([Chol][T...
Desenvolvimento de biomateriais ativos para engenharia de tecido muscular
Meira, Rafaela MarquesOs materiais eletroativos, nomeadamente os polímeros eletroativos piezoelétricos, têm sido utilizados no desenvolvimento de scaffolds para regeneração muscular pois conseguem mimetizar o ambiente biológico do tecido através de estímulos eletromecânicos. O polímero piezoelétrico poli(fluoreto de vinilideno) (PVDF) é um material muito promissor para a engenharia de tecidos devido à sua eletroatividade e biocompat...