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Serum dipeptidyl peptidase 4: a predictor of disease activity and prognosis in ...

Pinto-Lopes, Pedro; Afonso, Joana; Pinto-Lopes, Rui; Rocha, Catia; Lago, Paula; Goncalves, Raquel; Sousa, Helena Tavares; Macedo, Guilherme

Background: Serum dipeptidyl peptidase 4 (DPP-4) has drawn particular interest as a biomarker in inflammatory bowel disease (IBD), as this protease inactivates several peptides that participate in the inflammatory cascade. Methods: Two prospectively recruited cohorts consisting of 195 patients (101 had Crohn’s disease [CD] and 94 had ulcerative colitis [UC]) were evaluated using clinical indexes and followed up...

Date: 2020   |   Origin: Sapientia - Universidade do Algarve
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