2 documents found, page 1 of 1
Identification of primary drug resistance to rifampin in mycobacterium leprae s...
Mejía, Matilde Del Carmen Contreras; dos Santos, Maísa Porto; Silva, George Allan Villarouco da; Motta-Passos, Isabella da; Naveca, Felipe GomesThe aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multidrug resistance. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
Analysis of the immunological biomarker profile during acute zika virus infecti...
Naveca, Felipe Gomes; Pontes, Gemilson Soares; Chang, Aileen Yu Hen; Silva, George Allan Villarouco da; Nascimento, Valdinete Alves doBACKGROUND Infection with Zika virus (ZIKV) manifests in a broad spectrum of disease ranging from mild illness to severe neurological complications and little is known about Zika immunopathogenesis. OBJECTIVES To define the immunologic biomarkers that correlate with acute ZIKV infection. METHODS We characterized the levels of circulating cytokines, chemokines, and growth factors in 54 infected patients of both ...