4 documents found, page 1 of 1
Efeito do parasitismo por Trypanosoma cruzi sobre o potencial imunomodulatório ...
Melgaço Garcez, EmãnuellaDissertação (mestrado) — Universidade de Brasília, Faculdade de Medicina, Pós-graduação em Medicina Tropical, 2022.; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).; A doença de Chagas é uma infecção parasitária cujo agente etiológico é o protozoário hemoflagelado Trypanosoma cruzi. A doença impacta tecidos como a medula óssea e tecido adiposo, onde são encontradas as células-tronco mesenqu...
Faster cryptococcus melanization increases virulence in experimental and human ...
Sousa, Herdson Renney de; Oliveira Júnior, Getúlio Pereira de; Frazão, Stefânia de Oliveira; Gorgonha, Kaio César de Melo; Rosa, Camila PereiraCryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work, we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates and correlated them with patient data to better understand cryptococcosis. We collected 66 C. neoformans and 19 C. gattii clinical isolates and analyzed multiple virulence phenotypes and host–pathogen interaction outcomes. C. neofo...
Commentary : mesenchymal stem cells : a new piece in the puzzle of COVID-19 tre...
Carvalho, Juliana Lott; Melgaço Garcez, Emãnuella; Carvalho, Amandda Évelin Silva; Araujo, Felipe Saldanha deA Commentary on Mesenchymal Stem Cells: A New Piece in the Puzzle of COVID-19 Treatment By Saldanha-Araujo F, Melgaço Garcez E, Silva-Carvalho AE and Carvalho JL (2020). Front. Immunol. 11:1563. doi: 10.3389/fimmu.2020.01563.
Mesenchymal stem cells : a new piece in the puzzle of COVID-19 treatment
Araujo, Felipe Saldanha de; Melgaço Garcez, Emãnuella; Carvalho, Amandda Évelin Silva; Carvalho, Juliana LottCOVID-19 is a disease characterized by a strong inflammatory response in severe cases, which fails to respond to corticosteroid therapy. In the context of the current COVID-19 outbreak and the critical information gaps regarding the disease, several different therapeutic strategies are under investigation, including the use of stem cells. In the present manuscript, we provide an analysis of the rationale underl...