3 documents found, page 1 of 1
Veneno de Bothrops erythromelas ( Amaral, 1923 ) induz apoptose em células epit...
Sousa, Fabíola Carine Monteiro de; Jorge, Antônio Rafael Coelho; Menezes, Ramon Róseo Paula Pessoa Bezerra de; Torres, Alba Fabíola CostaBothrops erythromelas is responsible for a large number of snakebite incidents in Northeastern Brazil. Previously, we showed the effects of whole B. erythromelas venom in an isolated kidney model. To continue the study with B. erythromelas venom, the present work aims to study the effects of this venom on MDCK tubular epithelial cells and assess gene expression involved in kidney injury, aiming at elucidating t...
Estudo in vitro da atividade tripanocida da batroxicidina – catelecidina da glâ...
Mello, Clarissa PerdigãoChagas disease, also known as American trypanosomiasis, is a potentially fatal disease caused by the parasite Trypanosoma cruzi. There are two drugs available for the treatment of the disease, nifurtimox and benzonidazole. Both are toxic and have limited efficacy, requiring the search for new therapeutic alternatives. Antimicrobial peptides (AMPs) may be potential alternatives to conventional treatments already...
Antimicrobial effect of Dinoponera quadriceps (Hymenoptera: Formicidae) venom a...
Lima, Danya Bandeira; Torres, Alba Fabíola Costa; Mello, Clarissa Perdigão; Menezes, Ramon Róseo Paula Pessoa Bezerra; Sampaio, Tiago LimaAims: Dinoponera quadriceps venom (DqV) was examined to evaluate the antibacterial activity and its bactericidal action mechanism against Staphylococcus aureus. Methods and Results: DqV was tested against a standard strain of methicillinsensitive Staphylococcus aureus (MSSA), Staph. aureus ATCC 6538P and two standard strains of methicillin-resistant Staphylococcus aureus (MRSA), Staph. aureus ATCC 33591 and Sta...