11 documents found, page 1 of 2
Atherosclerotic Cardiovascular Disease, Unmet Needs, and Inclisiran
Ferreira, Jorge; Palma, Isabel; Pereira de Moura, José; Gouveia, Miguel; Corte-Real, Ana; Mello e Silva, AlbertoThe leading cause of death and disability worldwide aredue to atherosclerotic cardiovascular disease (ASCVD), entailing a heavy economic impact, in Portugal corresponding to 1% of the gross domestic product. The development and progression of ASCVD are closely related to hypercholesterolaemia, with high LDL-C levels being its most important and easily modifiable risk factor. Reducing LDL-C has been shown to dec...
Atherosclerosis in the primary health care setting: a real-word data study
Ascenção, Raquel; Alarcão, Joana; Araújo, Francisco; Costa, João; Fiorentino, Francesca; Gil, Victor; Gouveia, Miguel; Lourenço, FranciscoIntroduction and Objectives: To characterize patients with atherosclerosis, a disease with a high socioeconomic impact, in the Lisbon and Tagus Valley Health Region. Methods: A cross-sectional observational study was carried out through the Lisbon and Tagus Valley Regional Health Administration primary health care database, extracting data on the clinical and demographic characteristics and resource use of adul...
Atherosclerosis in the primary health care setting: a real-word data study
Ascenção, Raquel; Alarcão, Joana; Araujo, Francisco; Costa, João; Fiorentino, Francesca; Gil, Victor; Gouveia, Miguel; Lourenço, FranciscoIntroduction and objectives: To characterize patients with atherosclerosis, a disease with a high socioeconomic impact, in the Lisbon and Tagus Valley Health Region. Methods: A cross-sectional observational study was carried out through the Lisbon and Tagus Valley Regional Health Administration primary health care database, extracting data on the clinical and demographic characteristics and resource use of adul...
Os custos da aterosclerose em Portugal
Costa, João; Alarcão, Joana; Amaral‐Silva, Alexandre; Araújo, Francisco; Ascenção, Raquel; Caldeira, Daniel; Cardoso, Marta Ferreira; Correia, ManuelIntrodução e objetivos: As doenças cardiovasculares são a principal causa de morte em Portugal, sendo a aterosclerose o processo fisiopatológico subjacente mais comum. O objetivo deste estudo foi quantificar o impacto económico da aterosclerose em Portugal através da estimação dos custos associados. Métodos: A estimativa dos custos foi realizada na ótica da prevalência e na perspetiva da sociedade. A prevalênci...
Os custos da aterosclerose em Portugal
Costa, João; Alarcão, Joana; Amaral‐Silva, Alexandre; Araújo, Francisco; Ascenção, Raquel; Caldeira, Daniel; Cardoso, Marta Ferreira; Correia, ManuelIntrodução e objetivos: As doenças cardiovasculares são a principal causa de morte em Portu-gal, sendo a aterosclerose o processo fisiopatológico subjacente mais comum. O objetivo desteestudo foi quantificar o impacto económico da aterosclerose em Portugal através da estimac¸ãodos custos associados.Métodos: A estimativa dos custos foi realizada na ótica da prevalência e na perspetiva dasociedade. A prevalência ...
The burden of atherosclerosis in Portugal
Costa, João; Alarcão, Joana; Araujo, Francisco; Ascenção, Raquel; Caldeira, Daniel; Fiorentino, Francesca; Gil, Victor; Gouveia, MiguelAims: This paper sought to estimate the burden of disease attributable to atherosclerosis in mainland Portugal in 2016. Methods and results: The burden of atherosclerosis was measured in disability-adjusted life years (DALY) following the latest 2010 Global Burden of Disease (GBD) methodology. DALYs were estimated as the sum of years of life lost (YLL) with years lived with disability (YLD). The following clini...
Prospective Study of Methicillin-Resistant Staphylococcus aureus Colonization i...
Carvalho, Ana Sofia; Brás Monteiro, Filipa; Cruz, Inês; Monteiro, Nuno; Cardoso, Margarida; Mendes, Rita; Mello e Silva, AlbertoIntroduction: The infection by Staphylococcus aureus methicillin-resistant (MRSA) is one of the most important healthcare-associated infections. In 2014 there was a rule from the National Directorate of Health addressed to this problem.This study aims to quantify the patients with indication to search for MRSA colonization, examine the criteria, implicationsand possible strategies.Materials and Methods: Prospec...
Polyglandular autoimune syndrome Type 2 – case report
Malheiro, Filipa; Mendes, Rita; Santos, Eugénia; Mesquita, Teresa; Rocha, Isilda; Madruga, Isabel; Mello e Silva, AlbertoWe describe the clinical case of a 32-year-old woman with the previous diagnosis of thyroiditis, medicated with levothiroxin and with family history of hipothiroidism (sister).During the first trimester of pregnancy she begins the clinical picture of worsening weakness, incapability of weight gain (3Kg during whole pregnancy), alopecia and hyperpigmentation of the skin and mucosal surfaces. These symptoms persi...
Relapsing strokes as a manifestation of giant-cell arteritis
Luís, Patrícia; Pereira, João; Carvalho, Lucília; Mello e Silva, Alberto; Abecasis, PedroGiant-cell arteritis is a vasculitis that causes injury in small and medium calibre arteries, preferentially aorta and its cranial branches, what explains some of its classic symptoms (amaurosis, jaw claudication). There are, however, other manifestations to expect, so the authors present two clinical cases where diagnostic suspection was held by repeated strokes, simultaneously with a steady increase of severa...
Multiple endocrine neoplasia type 2B – clinical case
Mendes, Rita; Malheiro, Filipa; Santos, Eugénia; Gaspar, Isabel; Torrinha, Joaquim; Raposo, Luís; Madruga, Isabel; Mello e Silva, AlbertoWe report the case of a 19-year-old white male presenting marfanoid habitus, thickened corneal nerves, neuromas of the tongue and lips, skeletal abnormalities, nodular lesion of the adrenal gland, suggesting non-functioning adenoma, and syringomyelia, who was referred to the department of Internal Medicine to investigate a possible MEN2B syndrome. Medullary thyroid carcinoma with pulmonary and cervical lymph no...