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Exposure Scenarios for Estimating Contaminant Levels in Healthy Sustainable Die...

Ramos, H; Reis-Mendes, A; Silva, M; Ribeiro, M; Araújo, AM; Borges, C; Viegas, Olga; Melo, A; Martins, Z; Faria, MA; Ferreira, IMPLVO

<jats:p>Consumers are regularly exposed to well-known food contaminants (FCs), which are typically assessed for risk on an individual basis. However, there is limited knowledge about the overall levels and combinations of these compounds depending on dietary choices. The goal of this study was to estimate the real-life mixtures of FCs in different dietary models by integrating extensive data from the scientific...


Haute cuisine: A mixed-methods approach to assess gastronomic offer nutritional...

Pereira, M; Sousa, S; Melo, A; Padrão, P

In recent years, a growing interest of society for out-of-home food experiences has been observed, concurrently with an increasing number of restaurants associated to haute cuisine. However, data on the nutritional adequacy of the meals offered in these restaurants is lacking. This study aimed to evaluate the perception of haute cuisine chefs in Portugal about the importance attributed to food and nutrition rec...


From data to insight: Exploring contaminants in different food groups with lite...

Martins, E; Ramos, H; Araújo, AM; Silva, M; Ribeiro, M; Melo, A; Mansilha, C; Viegas, Olga; Faria, A; Ferreira, MPLVO

Food remains a major source of human exposure to chemical contaminants that are unintentionally present in commodities globally, despite strict regulation. Scientific literature is a valuable source of quantification data on those contaminants in various foods, but manually summarizing the information is not practicable. In this review, literature mining and machine learning techniques were applied in 72 foods ...


Mineralocorticoid receptor antagonists eplerenone and spironolactone modify adr...

Pereira, SS; Carvalho, LS; Costa, MM; Melo, A; Ferreira, IMPLVO; Gomez-Sanchez, CE; Monteiro, MP; Vinson, G; Pignatelli, D

Mineralocorticoid receptor antagonists (MRAs) are a class of anti-hypertensive drugs that act by blocking aldosterone action. The aim of this study was to evaluate whether the MRAs spironolactone and eplerenone influence adrenal cortical physiology and morphology. Spontaneous hypertensive rats (SHR, n = 18) and normotensive rats (WKY, n = 18) were randomly exposed to a daily dose of spironolactone (n = 6), eple...


Simultaneous determination of melatonin and trans-resveratrol in wine by disper...

Viegas, Olga; Esteves, C; Rocha, J; Melo, A; Ferreira, IMPLVO

The discovery of melatonin (Mel) in wines triggered a new interest in the paradigm of health benefits and wine consumption, usually ascribed to trans-resveratrol (trans-RSV). In this context, a dispersive liquid-liquid microextraction for the analysis of Mel and trans-RSV in wines by LC-FLD was developed. A 2(6-1) factorial design was used to identify the significant variables (p < 0.05) and Central Composite D...


Is food insecurity related to health-care use, access and absenteeism?

Melo, A; Matias, MA; Dias, SS; Gregório, Maria João; Rodrigues, AM; de Sousa, RD; Canhao, H; Perelman, J

Objective: Food insecurity (FI) is defined as uncertain access to healthy food in quantity and quality. We hypothesize that FI may be associated with greater health-care use and absenteeism because it may amplify the effect of diseases; also, FI may be associated with reduced health-care access because it reflects economic vulnerability. The present study estimates the association between FI and health-care use...


Trait determinants of impulsive behavior: a comprehensive analysis of 188 rats

Soares, AR; Esteves, M; Moreira, PS; Cunha, AM; Guimarães, MR; Carvalho, MM; Raposo-Lima, C; Morgado, P; Carvalho, AF; Coimbra, B; Melo, A

Impulsivity is a naturally occurring behavior that, when accentuated, can be found in a variety of neuropsychiatric disorders. The expression of trait impulsivity has been shown to change with a variety of factors, such as age and sex, but the existing literature does not reflect widespread consensus regarding the influence of modulating effects. We designed the present study to investigate, in a cohort of sign...


Uveítes

Coutinho, I; Brenardo, M; Lisboa, M; Melo, A; Furtado, A; Ferreira, I; Grima, B


Trabeculectomia modificada (Moorfields Safer Surgery - MSS): estudo da estabili...

Santos, C; Vaz, F; Ramalho, M; Pedrosa, C; Coutinho, I; Mota, M; Lisboa, M; Kaku, P; Melo, A

Objetivo: Estudar eventuais alterações na câmara anterior (CA) objectivadas com câmara de Scheimpflug (Oculus – Pentacam®) por comparação do olho a ser operado e/ou adelfo com as alterações obtidas no pós-operatório precoce após a realização de trabeculectomia segundo uma técnica modificada – Moorfields Safer Surgery (Trab MSS). Métodos: Trab MSS – Realizou-se trabeculectomia com flap conjuntival de base fórnix...


Anestesia em oftalmologia

Ramalho, M; Laranjo, J; Vaz, F; Pina, S; Santos, C; Pedrosa, C; Coutinho, I; Mota, M; Melo, A

Descrevem-se as várias técnicas anestésicas usadas em oftalmologia. História, indicações e diferentes tipos de anestesia.


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