24 documents found, page 1 of 3
RSV-Bacterial Co-Infection Is Associated With Increased Illness Severity in Hos...
Torres, Ana Rita; Gaio, Vânia; Melo, Aryse; Lança, Miguel; Barreto, Marta; Lagoa Gomes, Licínia Isabel; Azevedo, Inês; Bandeira, Teresa; Lito, DavidDuring the autumn/winter respiratory syncytial virus (RSV) epidemics, bacterial co-infection is common and affects the disease severity. We aimed to understand the relationship between RSV-bacterial co-infections and clinical severity since the RSV seasonality change after COVID-19 pandemic. We conducted a prospective, sentinel surveillance study at 20 sites in Portugal in children under 2 years hospitalized wi...
COVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 BA...
Lanièce Delaunay, Charlotte; Martínez-Baz, Iván; Sève, Noémie; Domegan, Lisa; Mazagatos, Clara; Buda, Silke; Meijer, Adam; Kislaya, IrinaBackground: Scarce European data in early 2021 suggested lower vaccine effectiveness (VE) against SARS-CoV-2 Omicron lineages than previous variants. Aim: We aimed to estimate primary series (PS) and first booster VE against symptomatic BA.1/BA.2 infection and investigate potential biases. Methods: This European test-negative multicentre study tested primary care patients with acute respiratory symptoms for SAR...
Early COVID‐19 XBB.1.5 Vaccine Effectiveness Against Hospitalisation Among Adul...
Antunes, Liliana; Mazagatos, Clara; Martínez‐Baz, Iván; Naesens, Reinout; Borg, Maria‐Louise; Petrović, Goranka; Fatukasi, Terra; Jancoriene, LigitaWe conducted a multicentre test-negative case–control study covering the period from October 2023 to January 2024 among adult patients aged ≥18 years hospitalised with severe acute respiratory infection in Europe. We provide early estimates of the effectiveness of the newly adapted XBB.1.5 COVID-19 vaccines against PCR-confirmed SARS-CoV-2 hospitalisation. Vaccine effectiveness was 49% overall, ranging between ...
Influenza vaccine effectiveness in Europe: Results from the 2022–2023 VEBIS (Va...
Maurel, Marine; Pozo, Francisco; Pérez‐Gimeno, Gloria; Buda, Silke; Sève, Noémie; Oroszi, Beatrix; Hooiveld, Mariette; Gómez, Verónica; Domegan, LisaBackground: Influenza A(H3N2) viruses dominated early in the 2022-2023 influenza season in Europe, followed by higher circulation of influenza A(H1N1)pdm09 and B viruses. The VEBIS primary care network estimated the influenza vaccine effectiveness (VE) using a multicentre test-negative study. Materials and methods: Primary care practitioners collected information and specimens from patients consulting with acut...
Effectiveness of the adapted bivalent mRNA COVID-19 vaccines against hospitalis...
Antunes, Liliana; Mazagatos, Clara; Martínez-Baz, Iván; Gómez, Verónica; Borg, Maria-Louise; Petrović, Goranka; Duffy, Róisín; Dufrasne, François EThe European Medicines Agency (EMA) authorised four adapted bivalent mRNA COVID-19 vaccines for use against COVID-19 in September/October 2022: Comirnaty (BNT162b2; Pfizer-BioNTech) and Spikevax (mRNA-1273; Moderna) Original/Omicron BA.1 and Original/Omicron BA.4–5 [1]. During autumn 2022, all European Union/European Economic Area (EU/EEA) countries had vaccination campaigns in place to administer a booster dos...
Respiratory syncytial virus under 2 years of age: hospitalization trends and ri...
Torres, Ana Rita; Melo, Aryse; Aniceto, Carlos; Guiomar, Raquel; Gaio, Vânia; Bandeira, Teresa; Azevedo, Inês; Rodrigues, Ana PaulaIntroduction and Objectives: Respiratory Syncytial Virus (RSV) infection is an important cause of hospitalization in children under five years. A national RSV sentinel network was set up in Portugal in April 2021. We describe the trends in RSV hospitalizations until September 2022 and identify risk factors for severe disease. Methods: Acute respiratory infections in hospitalized children under two years were re...
Programa Nacional de Vigilância da Gripe: relatório da época 2022/2023
Verdasca, Nuno; Melo, Aryse; Henriques, Camila; Gomes, Licínia; Lança, Miguel; Dias, Daniela; Silva, Susana Pereira da; Rodrigues, Ana PaulaRelatório anual do Programa Nacional de Vigilância da Gripe (PNVG). A presente publicação descreve a caraterização clínica e laboratorial da atividade gripal na época 2022/2023. O PNVG assegura a vigilância epidemiológica da gripe em Portugal, integrando as componentes de vigilância clínica e laboratorial. A componente clínica possibilita o cálculo de taxas de incidência permitindo descrever a intensidade e evo...
Resurgence of Respiratory Syncytial Virus in Children: An Out-of-Season Epidemi...
Torres, Ana Rita; Guiomar, Raquel Guiomar; Verdasca, Nuno; Melo, Aryse; Rodrigues, Ana PaulaIntroduction: An out-of-season increase in respiratory syncytial virus (RSV) incidence was observed in Portugal from June 2021 onwards, revealing a continuing surge in cases throughout 2021/2022 autumn/winter. We aimed to describe this out-of-season epidemic and define its epidemic period, by analysing RSV incidence from week 40 of 2020 (2020-W40) to week 18 of 2022 (2022-W18).Material and Methods: Surveillance...
Vigilância do vírus sincicial respiratório em Portugal - VigiRSV
Azevedo, Inês; Rodrigues, Ana Paula; Gaio, Vânia; Melo, Aryse; Guiomar, Raquel; Equipa VigiRSVEste trabalho descreve os principais resultados da vigilância das infeções por VSR em Portugal na época 2022/23.
Results of the Portuguese EQA program for molecular detection of SARS-CoV-2, 20...
Correia, Helena; Silva, Susana; Ventura, Catarina; Melo, Aryse; Guiomar, Raquel; Faria, Ana PaulaThe initial strategy for containing the spread of SARS CoV 2 was the prompt identification of COVID 19 cases. National Reference laboratory implemented the biomolecular assays to detect SARS-CoV-2. In June 2020 the Portuguese National External Quality Assessment Program (PNAEQ) in collaboration with National Reference Laboratory for Influenza and Other Respiratory Viruses (NRL) organized the first National Exte...