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Topical HPMC/S-nitrosoglutathione solution decreases inflammation and bone reso...
Martins, Conceição S.; Leitão, Renata Ferreira de Carvalho; Melo, Iracema M.; Santos, Glaylton S. Santo; Baldim, Victor Baldim; Bonfim, Luana E.S-nitrosoglutathione (GSNO) is a nitric oxide (NO) donor, which exerts antioxidant, anti-inflammatory, and microbicidal actions. Intragingival application of GSNO was already shown to decrease alveolar bone loss, inflammation and oxidative stress in an experimental periodontal disease (EPD) model. In the present study, we evaluated the potential therapeutic effect of topical applications of hydroxypropylmethylc...
Date: 2016
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Origin: Oasisbr