2 documents found, page 1 of 1
Differential gene transcription, biochemical responses, and cytotoxicity assess...
Serrano, Miguel A. S.; Gonzalez-Rey, Maria; Mattos, Jacó J.; Flores-Nunes, Fabrício; Mello, Álvaro C. P.; Zacchi, Flávia L.; Piazza, Clei E.Pharmaceuticals, such as anti-inflammatory nonsteroidal drugs, are frequently detected in aquatic ecosystems. Studies about the effects of these substances in nontarget organisms, such as bivalves, are relevant. The aim of this study was to evaluate the effects on antioxidant status caused by ibuprofen (IBU) in oysters Crassostrea gigas exposed for 1, 4, and 7 days at concentrations 1 and 100 μg L(-1). Levels o...
Changes in protein expression of pacific oyster Crassostrea gigas exposed in si...
Flores-Nunes, Fabrício; Gomes, Tânia; Company, Rui; Moraes, Roberta R. M.; Sasaki, Silvio T.; Taniguchi, Satie; Bicego, Márcia C.; Melo, Cláudio M. R.The composition and concentration of substances in urban effluents are complex and difficult to measure. These contaminants elicit biological responses in the exposed organisms. Proteomic analysis is a powerful tool in environmental toxicology by evidencing alterations in protein expression due to exposure to contaminants and by providing a useful framework for the development of new potential biomarkers. The a...