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Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice...

Citó, M. C. O.; Silva, Maria Izabel Gomes; Santos, Luciana Kelly Ximenes; Fernandes, M. L.; Melo, Francisca Helvira Cavalcante

Hoodia gordonii is a plant species used traditionally in southern Africa to suppress appetite. Recently, it has been associated with a significant increase in blood pressure and pulse rate in women, suggesting sympathomimetic activity. The present study investigated the possible antidepressant-like effects of acute and repeated (15 days) administration of H. gordonii extract (25 and 50 mg/kg, po) to mice expose...

Date: 2015   |   Origin: Oasisbr

Investigação de possíveis mecanismos de ação ansiolítico, antidepressivo e anal...

Melo, Francisca Helvira Cavalcante

Carvacrol (5-Isopropyl-2-methylphenol) is a monoterpenic phenol present in the essencial oil of many plants. It is the major component of the essential oil fraction of oregano and thyme. Knowing the antidepressant and anxiolytic actions of carvacrol, this work presents an analysis of monoamines and amino acids concentrations in mice striatum after oral treatment with carvacrol at doses of 25 and 50 mg / Kg. The...

Date: 2015   |   Origin: Oasisbr

Profile of temporomandibular disorder patients submitted to dental and physioth...

Fernandes, Mariana Lima; Marques, Lídia Audrey Rocha Valadas; Rodrigues Neto, Edilson Martins; Lotif, Mara Assef Leitão

Introduction: Temporomandibular disorder (TMD) is the term used in Dentistry to define the structural and disorder changes affect the physiology of the masticatory system composed of TMJ and related to musculoskeletal structures. Objective: To conduct a descriptive, transversal and documentary study aiming to determine the profile of 14 TMD patients undergoing simultaneous dental and physiotherapeutic treatment...

Date: 2014   |   Origin: Oasisbr

Antinociceptive activity of carvacrol (5-isopropyl-2- methylphenol) in mice

Melo, Francisca Helvira Cavalcante; Rios, Emiliano Ricardo Vasconcelos; Rocha, Nayrton Flávio Moura; Citó, Maria do Carmo de Oliveira

Objectives Carvacrol (5-isopropyl-2-methylphenol) is a monoterpenic phenol which is present in the essential oil of oregano and thyme.We have investigated the behavioural effects of carvacrol in animal models of pain, such as acetic acidinduced abdominal constriction, formalin and hot-plate tests in mice. The spontaneous motor activity of animals treated with carvacrol was investigated using open-field and rota...

Date: 2013   |   Origin: Oasisbr

Investigação da ação central do carvacrol em modelos de ansiedade, depressão e ...

Melo, Francisca Helvira Cavalcante

Carvacrol (5-Isopropyl-2-methylphenol) is a monoterpenic phenol present in the essencial oil of many plants. It is the major component of the essential oil fraction of oregano and thyme. This work presents the behavioral effects of carvacrol in animal models of anxiety, depression, sedation and convulsion, such as, elevated plus maze (EPM), open field, rota rod, barbiturate-induced sleeping time, pentilenetetra...

Date: 2012   |   Origin: Oasisbr

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