3 documents found, page 1 of 1
Stemodia maritima L. extract decreases inflammation, oxidative stress, and alve...
Teixeira, Alrieta H.; Freire, Jordânia M. de Oliveira; Sousa, Luzia H. T. de; Parente, Antônia T.; Sousa, Nayara A. de; Arriaga, Angela M. C.Periodontitis is very prevalent worldwide and is one of the major causes of tooth loss in adults. About 80% of the worldwide population use medicinal plants for their health care. Stemodia maritima L. (S. maritima) antioxidant and antimicrobial effects in vitro as well as anti-inflammatory properties. Herein, the potential therapeutic effect of S. maritima was assessed in rats subjected to experimental periodon...
Topical HPMC/S-nitrosoglutathione solution decreases inflammation and bone reso...
Martins, Conceição S.; Leitão, Renata Ferreira de Carvalho; Melo, Iracema M.; Santos, Glaylton S. Santo; Baldim, Victor Baldim; Bonfim, Luana E.S-nitrosoglutathione (GSNO) is a nitric oxide (NO) donor, which exerts antioxidant, anti-inflammatory, and microbicidal actions. Intragingival application of GSNO was already shown to decrease alveolar bone loss, inflammation and oxidative stress in an experimental periodontal disease (EPD) model. In the present study, we evaluated the potential therapeutic effect of topical applications of hydroxypropylmethylc...
Effect of alendronate on bone-specific alkaline phosphatase on periodontal bone...
Goes, Paula; Melo, Iracema M.; Dutra, Caio S.; Lima, Ana Patrícia S.; Lima, VilmaObjective: The study aims to evaluate the effect of alendronate (ALD) on bone-specific alkaline phosphatase (BALP) serum levels on periodontal bone loss in Wistar rats. Design: Periodontitis was induced by ligature around the upper second molar in 36 male Wistar rats ( 200 g). Groups of six animals received 0.9% saline (SAL) or ALD (0.01; 0.05; 0.25 mg kg 1, s.c.), over 11 days; then they were sacrificed and th...