2 documents found, page 1 of 1
Versatility of chitosan-based biomaterials and their use as scaffolds for tissu...
Ribeiro, José Carlos Viana; Vieira, Rodrigo Silveira; Melo, Iracema Matos; Araújo, Vilana Maria Adriano; Lima, VilmaChitosan is a naturally occurring polysaccharide obtained from chitin, present in abundance in the exoskeletons of crustaceans and insects. It has aroused great interest as a biomaterial for tissue engineering on account of its biocompatibility and biodegradation and its affinity for biomolecules. A significant number of research groups have investigated the application of chitosan as scaffolds for tissue regen...
Low-dose combination of alendronate and atorvastatin reduces ligature-induced a...
Dutra, Paula Goes Pinheiro; Melo, Iracema Matos; Silva, Luana Maria Castelo Melo; Benevides, Norma Maria Barros; Alencar, Nylane Maria Nunes deMaterial and Methods: Periodontitis was induced by ligature in 78 Wistar rats. Groups of six rats prophylactically received 0.9% saline (SAL), ALD (0.01 or 0.25 mg/kg subcutaneously) or ATV (0.3 or 27 mg/kg by gavage). Then, groups of six rats received the combination of ALD+ATV (0.25 mg/kg + 27 mg/kg, 0.01 mg/ kg + 0.3 mg/kg, 0.25 mg/kg + 0.3 mg/kg or 0.01 mg/kg + 27 mg/kg) prophylactically. An extra group of ...