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Treatment with Saccharomyces boulardii reduces the inflammation and dysfunction...
Justino, Priscilla F. C.; Melo, Luis F. M.; Nogueira, Andre F.; Costa, Jose V. G.; Silva, Luara M. N.; Santos, Cecila M.; Mendes, Walber O.Intestinal mucositis is an important toxic side effect of 5-fluorouracil (5-FU) treatment. Saccharomyces boulardii is known to protect from intestinal injury via an effect on the gastrointestinal microbiota. The objective of the present study was to evaluate the effect of S. boulardii on intestinal mucositis induced by 5-FU in a murine model. Mice were divided into saline, saline (control) þ 5-FU or 5-FU þ S. b...
Date: 2014
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Origin: Oasisbr