32 documents found, page 1 of 4
Glossectomia Total na Era de Preservação de Órgão - Resultados Funcionais e Sob...
Pereira, S; Fino, R; Montalvão, P; Mariano, M; Melo, M; Castelhano, L; Magalhães, MObjetivos: Avaliação de doentes submetidos a glossectomia total (GT). Material e Métodos: Estudo retrospetivo que incluiu os doentes submetidos a GT entre 2009 e 2018 no serviço de Otorrinolaringologia do IPOLFG. Resultados: Foram incluídos 27 doentes. A vasta maioria dos doentes (78%) apresentava tumor em estadio avançado (IV). A GT foi realizada como tratamento de resgate em 56% dos casos. A reconstrução foi ...
Heterogeneity Amongst GLP-1 RA Cardiovascular Outcome Trials Results: Can Defin...
Melo, M; Gavina, C; Silva-Nunes, J; Andrade, L; Carvalho, DAtherosclerotic cardiovascular diseases are the leading cause of adverse outcomes in patients with type 2 diabetes, and all new anti-diabetic agents are mandated to undergo cardiovascular outcome trials (CVOTs). Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are incretin mimetics that reduce blood glucose levels with a low associated risk of hypoglycaemia. CVOTs with different GLP-1 RAs yielded different ...
Genetic determinants for prediction of outcome of patients with papillary thyro...
Póvoa, AA; Teixeira, E; Bella-cueto, MR; Batista, R; Pestana, A; Melo, M; Alves, T; Pinto, M; Sobrinho-Simões, M; Maciel, J; Soares, PPapillary thyroid carcinoma (PTC) usually presents an excellent prognosis, but some patients present with aggressive metastatic disease. BRAF, RAS, and TERT promoter (TERTp) genes are altered in PTC, and their impact on patient outcomes remains controversial. We aimed to determine the role of genetic alterations in PTC patient outcomes (recurrent/persistent disease, structural disease, and disease-specific mort...
Heterogeneity amongst GLP-1 RA cardiovascular outcome trials results: can defin...
Melo, M; Gavina, C; Silva-Nunes, J; Andrade, L; Carvalho, DAtherosclerotic cardiovascular diseases are the leading cause of adverse outcomes in patients with type 2 diabetes, and all new anti-diabetic agents are mandated to undergo cardiovascular outcome trials (CVOTs). Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are incretin mimetics that reduce blood glucose levels with a low associated risk of hypoglycaemia. CVOTs with different GLP-1 RAs yielded different ...
Portuguese-Brazilian Evidence-Based Guideline on the Management of Hyperglycemi...
Bertoluci, M; Nunes Salles, JE; Silva-Nunes, J; Cordeiro Pedrosa, H; Moreira, R; Calado da Silva Duarte, R; Maurício da Costa Carvalho, D; Trujilho, FBackground: In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and Portugal was established to develop an evidence-based guideline for treatment of hyperglycemia in T2DM. Methods: MEDLINE (via PubMed) was searched for randomized clinical trials, meta-analyses...
Clinicopathological features as prognostic predictors of poor outcome in papill...
Póvoa, AA; Teixeira, E; Bella-Cueto, MR; Melo, M; Oliveira, MJ; Sobrinho-Simões, M; Maciel, J; Soares, PPapillary thyroid cancer (PTC) has an indolent nature and usually excellent prognosis. Some PTC clinicopathological features may contribute to the development of aggressive metastatic disease. In this work, we want to evaluate PTC clinicopathological features that are presurgical prognostic predictors of patients’ outcomes and find which indicators are more adequate for tailoring surgical procedures and follow-...
Portuguese-Brazilian evidence-based guideline on the management of hyperglycemi...
Bertoluci, MC; Salles, JEN; Silva-Nunes, J; Pedrosa, HC; Moreira, RO; Silva Duarte, RMC; Carvalho, D; Trujilho, FR; Santos Raposo, JFC; Parente, EBBackground: In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and Portugal was established to develop an evidence-based guideline for treatment of hyperglycemia in T2DM. Methods: MEDLINE (via PubMed) was searched for randomized clinical trials, meta-analyses...
Adult-onset autoimmune diabetes: comparative analysis of classical and latent p...
Fadiga, L; Saraiva, J; Catarino, D; Frade, J; Melo, M; Paiva, IIntroduction: Adult-onset autoimmune diabetes (AID) has two different phenotypes: classic type 1 diabetes mellitus (T1DM), with insulin requirement just after diagnosis, and latent autoimmune diabetes in adults (LADA). The purpose of this study is to characterize patients with AID followed on a tertiary centre, comparing classic T1DM and LADA. Methods: We collected data from patients with diabetes and positive ...
Temporal trend of tuberculosis in Brazil
Melo, M; Barros, H; Donalisio, MRThe objective was to analyze the temporal trend of tuberculosis incidence rates in Brazilian states and regions to identify patterns and inequalities. We carried out an ecological study of incidence rates per 100,000 inhabitants aged between 20 and 59 years with tuberculosis in Brazil and in their respective states from 2001 to 2017 according to annual percentage change and joinpoint regression. A significant d...
Perfil Terapêutico da Hipertensão da Rede de Médicos Sentinela
Martins, AP; Melo, M; Mendes, Z; Ferreira, AP; Miranda, AC; Falcão, IM; Domingues, JC; Goucha, PObjectivosDescrever o perfil terapêutico da hipertensão na Rede de Médicos Sentinela e analisar o padrão de prescrição dos anti-hipertensores de acordo com a forma de hipertensão e co-morbilidades. Tipo de estudoEstudo transversal LocalRede de Médicos-Sentinela de Portugal População Doentes hipertensos que se deslocaram á consulta entre 15 de Setembro e 30 de Outubro de 1998, à excepção de doentes menores de 18...