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Fiber optic realshape in endovascular aneurysm repair: following the light into...

Melo, Ryan; Pedro, Luís M

Klaassen et al. conducted a retrospective observational matched cohort study comparing patients undergoing endovascular aneurysm repair (EVAR) with or without the use of Fiber Optic RealShape (FORS) technology. They compared the use of FORS during contralateral gate cannulation in 27 cases matched (age, sex, and body mass index) with 27 patients using regular (fluoroscopy only) EVAR. The results indicated a red...


Aortic risk scoring gets a PATENTed solution: debate on remodelling after aorti...

Spath, Paolo; Melo, Ryan

In their recent study, Shen and colleagues aimed to provide a new tool to forecast the evolution of type B aortic dissection (TBAD), particularly regarding risk assessment for aortic remodelling and diameter evolution. While there is consensus on managing complicated acute TBAD, the approach to uncomplicated dissections remains controversial. Current guidelines suggest that specific factors should or may be con...


The importance of quality of life in aortic research

Melo, Ryan; Twine, Christopher P.

Acute type B aortic dissections have for long been considered the benign aortic dissection. In contrast to type A aortic dissections, most patients do not require immediate surgical repair and are able to survive the acute event under strict medical therapy. Unfortunately, the relatively good short term results are counterbalanced by a high rate of late aortic complications and death. People who develop an aort...


The evolution of management of type B aortic dissection in a series of 100 cons...

Lopes, Alice; Pedro, Luís M; Melo, Ryan; Moutinho, Mariana; Sobrinho, Gonçalo; Amorim, Pedro; Silvestre, Luís; Fernandes E Fernandes, Ruy

Introduction and objectives: Management of aortic dissection is rapidly evolving. The present study aims to assess paradigm shifts in type B aortic dissection (TBAD) treatment modalities and their outcomes according to clinical presentation and type of treatment. We also aim to assess the impact of endovascular technology in TBAD management in order to define organizational strategies to provide an integrated c...


A systematic review and meta-analysis of the incidence of acute aortic dissecti...

Melo, Ryan; Oliveira Mourão, Mariana; Caldeira, Daniel; Alves, Mariana; Lopes, Alice; Duarte, António; Fernandes E Fernandes, Ruy; Pedro, Luís M

Objective: To perform a systematic review and meta-analysis of all population-based studies reporting on incidence of acute aortic dissections (AADs). Methods: We searched the MEDLINE, EMBASE, CENTRAL, and Open Grey databases from inception to August 2020 for population-based studies reporting on the incidence of AAD. A systematic review was conducted following the PRISMA guidelines using a registered protocol ...


Incidence of acute aortic dissections in patients with out of hospital cardiac ...

Melo, Ryan; Machado, Carolina; Caldeira, Daniel; Alves, Mariana; Lopes, Alice; Serrano, Maria; Fernandes E Fernandes, Ruy; Pedro, Luís M

Objectives: Acute Aortic dissection (AAD) may present as out-of-hospital cardiac arrest (OHCA). However, the incidence of this presentation is not well known. Our aim was to perform a systematic review and meta-analysis of all observational studies reporting on the incidence of AAD in patients with OHCA. Methods: We searched MEDLINE, CENTRAL, PsycInfo, Web of Science Core Collection and OpenGrey databases from ...


The impact of the proctor assistance for a safe learning curve in the developme...

Melo, Ryan; Fernandes E Fernandes, Ruy; Salvado, Margarida; Duarte, Antonio; Lopes, Alice; Verhoeven, Eric; Fernandes E Fernandes, Jose; Pedro, Luís M

Introduction: Initiating an endovascular aortic program for treatment of complex aortic aneurysms with fenestrated and branched grafts (FB-EVAR) is challenging. Using a Proctor is one option for training and development of the team. However, this approach has not been formally analyzed. The aim of this study was to analyze the learning curve and the effect of the Proctor regarding safety and effectiveness in FB...


Incidence and prevalence of thoracic aortic aneurysms: a systematic review and ...

Melo, Ryan; Duarte, Gonçalo Silva; Lopes, Alice; Alves, Mariana; Caldeira, Daniel; Fernandes E Fernandes, Ruy; Pedro, Luís M

Thoracic aortic aneurysms (TAA) may grow asymptomatically until they rupture, with a mortality over 90%. The true incidence and prevalence of this condition is uncertain and epidemiologic data is scarce, understudied and dispersed. Therefore, we aimed to conduct a systematic review and meta-analysis of the incidence and prevalence of TAAs in population-based studies. We searched MEDLINE, EMBASE and CENTRAL from...


Does autosomal dominant polycystic kidney disease increase the risk of aortic a...

Nunes, Raquel; Melo, Ryan; Almeida, Ana G.; Almeida, Edgar; Pinto, Fausto J.; Pedro, Luís M; Caldeira, Daniel

Autosomal Dominant Polycystic Kidney Disease (ADPKD) has several renal and extra-renal manifestations. Studies have reported a higher incidence of aortic aneurysms (AAs)/aortic dissections (ADs) in these patients, and we believe ADPKD should be considered as a risk factor for AA/AD. In order to support our opinion we conducted a systematic review and meta-analysis analyzing the risk of AA/AD in ADPKD patients.W...


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