54 documents found, page 1 of 6
Gelidium corneum and its solid by-product from agar extraction are sources of h...
Batista, Joana; Lopes, Diana; Neves, Bruna B.; Pais, Ana Rita; Pinho, Marisa; Moreira, Ana S. P.; Conde, Tiago; Bonciarelli, Stefano; Goracci, LauraThe red alga Gelidium corneum is commonly harvested for agar extraction, producing significant biomass residue that remains underutilized. Gelidium corneum and its residue represent promising sources of high-value compounds, including lipid ingredients, encompassing omega-3 and omega-6 polyunsaturated fatty acids, with potential applications in foods and cosmetics. Algae lipids are quite diverse and complex, ho...
Bioactive lipids in Dunaliella salina: implications for functional foods and he...
Pais, Rita; Conde, Tiago; Neves, Bruna B.; Pinho, Marisa; Coelho, Marta; Pereira, Hugo; Rodrigues, Alexandre M. C.; Domingues, Pedro; Gomes, Ana MariaDunaliella salina is a green microalga extensively explored for β-carotene production, while knowledge of its lipid composition is still limited and poorly investigated. Among lipids, polar lipids have been highlighted as bioactive phytochemicals with health-promoting properties. This research aimed to provide an in-depth lipidome profiling of D. salina using liquid and gas chromatography coupled with mass spec...
Bioactive lipids in : implications for functional foods and health
Pais, Rita; Conde, Tiago; Neves, Bruna B.; Pinho, Marisa; Coelho, Marta; Pereira, Hugo; Rodrigues, Alexandre M. C.; Domingues, Pedro; Gomes, Ana MariaDunaliella salina is a green microalga extensively explored for β-carotene production, while knowledge of its lipid composition is still limited and poorly investigated. Among lipids, polar lipids have been highlighted as bioactive phytochemicals with health-promoting properties. This research aimed to provide an in-depth lipidome profiling of using liquid and gas chromatography coupled with mass spectrometry. ...
Lipidome of extracellular vesicles from Giardia lamblia
Faria, Clarissa Perez; Ferreira, Bárbara; Lourenço, Ágata; Guerra, Inês Calado; Melo, Tânia; Domingues, Pedro; Domingues, Maria do Rosário MarquesExtracellular vesicles (EVs) (exossomes, microvesicles and apoptotic bodies) have been well acknowledged as mediators of intercellular communications in prokaryotes and eukaryotes. Lipids are essential molecular components of EVs but at the moment the knowledge about the lipid composition and the function of lipids in EVs is limited and as for now none lipidomic studies in Giardia EVs was described. Therefore, ...
Lipid profile variability in children at different ages measured in dried blood...
Ferreira, Helena Beatriz; Melo, Tânia; Rocha, Hugo; Paiva, Artur; Domingues, Pedro; Domingues, M. RosárioDried blood spot (DBS) is a minimally invasive sampling technique that has several advantages over conventional venipuncture/arterial blood sampling. More recently, DBS has also been applied for lipidomics analysis, but this is an area that requires further research. The few works found in the literature on lipidomics of DBS samples performed the analysis in adult samples, leaving pediatric ages unmapped. The o...
Evaluation of Lipid Extracts from the Marine Fungi Emericellopsis cladophorae a...
Abraúl, Mariana; Alves, Artur; Hilário, Sandra; Melo, Tânia; Conde, Tiago; Domingues, Maria Rosário; Rey, FelisaMarine environments occupy more than 70% of the earth's surface, integrating very diverse habitats with specific characteristics. This heterogeneity of environments is reflected in the biochemical composition of the organisms that inhabit them. Marine organisms are a source of bioactive compounds, being increasingly studied due to their health-beneficial properties, such as antioxidant, anti-inflammatory, antib...
Light modulates the lipidome of the photosynthetic sea slug Elysia timida
Rey, Felisa; Cartaxana, Paulo; Aveiro, Susana; Greenacre, Michael; Melo, Tânia; Domingues, Pedro; Domingues, M. Rosário; Cruz, SóniaLong-term kleptoplasty, the capability to retain functional stolen chloroplasts (kleptoplasts) for several weeks to months, has been shown in a handful of Sacoglossa sea slugs. One of these sea slugs is Elysia timida, endemic to the Mediterranean, which retains functional chloroplasts of the macroalga Acetabularia acetabulum. To understand how light modulates the lipidome of E. timida, sea slug specimens were s...
Mitochondrial fatty acid β-oxidation disorders: from disease to lipidomic studi...
Guerra, Inês M. S.; Ferreira, Helena B.; Melo, Tânia; Rocha, Hugo; Moreira, Sónia; Diogo, Luísa; Domingues, Maria Rosário; Moreira, Ana S. P.Fatty acid oxidation disorders (FAODs) are inborn errors of metabolism (IEMs) caused by defects in the fatty acid (FA) mitochondrial β-oxidation. The most common FAODs are characterized by the accumulation of medium-chain FAs and long-chain (3-hydroxy) FAs (and their carnitine derivatives), respectively. These deregulations are associated with lipotoxicity which affects several organs and potentially leads to l...
Bioprospecting bioactive polar lipids from olive (Olea europaea cv. Galega vulg...
Alves, Eliana; Rey, Felisa; Melo, Tânia; Barros, Madalena P.; Domingues, Pedro; Domingues, RosárioOlive seeds have been considered as a new nutritionally healthy food supplement. They are rich in monounsaturated n-9 and essential polyunsaturated n-6 lipids. However, little is known about their polar lipids, potentially bioactive and chemical identity markers for olive pulp and oil. This work aimed to identify the polar lipidome of olive seeds to find possible bioactive compounds and markers of geographic or...
Lipidomics of common octopus’ (Octopus vulgaris) arm muscle using untargeted hi...
Gaspar, Luís; Ricardo, Fernando; Melo, Tânia; Domingues, Pedro; Domingues, Rosário; Calado, Ricardo; Rey, FelisaThe common octopus, Octopus vulgaris, is one of the most important cephalopod fisheries in the world. In Mediterranean cuisine, the common octopus is perceived as an ingredient highly valued for its palatability and nutritional value (source of omega 3 fatty acids). However, the polar lipids of this species are still poorly understood. The present study performed the first fingerprinting of the polar lipidome o...