2 documents found, page 1 of 1
Isolation and Identification of Cytotoxic Compounds Present in Biomaterial Life®
Ferreira, Maria Beatriz; Pereira, Nelson A. M.; Marto, Carlos Miguel; Cardoso, Miguel; Amaro, Inês; Coelho, Ana; Saraiva, José; Spagnuolo, GianricoDirect pulp capping consists of a procedure in which a material is directly placed over the exposed pulp to maintain dental vitality. Although still widely used in clinical practice, previous in vitro studies found that the biomaterial Life® presented high cytotoxicity, leading to cell death. This study aimed to identify the Life® constituents responsible for its cytotoxic effects on odontoblast-like cells (MDP...
Conformational Behavior of Dimethyl 5-Methyl-1H,3H-pyrrolo[1,2-c][1,3]thiazole-...
Kaczor, A.; Melo, T. M. V. D. Pinho e; Soares, M. I. L.; Fausto, R.The structure of dimethyl 5-methyl-1H,3H-pyrrolo[1,2-c][1,3]thiazole-6,7-dicarboxylate 2,2-dioxide (PTD) was investigated in low-temperature noble gas matrixes (Ar, Kr, Xe), amorphous solid, and the crystalline state by infrared spectroscopy and computational methods. The geometry of PTD conformers is defined by the orientation of two methyl ester groups, which may adopt pseudo-trans or pseudo-cis positions in ...