6 documents found, page 1 of 1
The role of MHC haplotypes H2d/H2b in mouse resistance/susceptibility to cyst f...
Resende,Marianne G.; Fux,Blima; Caetano,Brália C.; Mendes,Erica A.; Silva,Neide M.; Ferreira,Adriana M.; Melo,Maria Norma; Vitor,Ricardo W.A.Toxoplasma gondii strains displaying the Type I/III genotype are associated with acquired ocular toxoplasmosis in humans. Here, we used a mice model to characterize some immunological mechanisms involved in host resistance to infection with such strains. We have chosen the Type I/III strains D8, G2 and P-Br, which cause a chronic infection in mice that resembles human toxoplamosis. Mice deficient of molecules M...
Leishmaniose tegumentar americana: apresentação pouco comum
Guedes,Antonio Carlos Martins; Carvalho,Maria de Lourdes R. de; Melo,Maria NormaRelata-se caso de leishmaniose tegumentar americana com lesões proeminentes na face. Os critérios diagnósticos incluíram dados clínicos e epidemiológicos, intradermorreação de Montenegro, identificação de Leishmania pela reação em cadeia da polimerase e resposta clínica ao tratamento. A importância do relato se deve ao fato de se tratar de caso incomum de leishmaniose tegumentar americana.
Diagnosing human asymptomatic visceral leishmaniasis in an urban area of the St...
Moreno,Elizabeth Castro; Melo,Maria Norma; Lambertucci,José Roberto; Serufo,José Carlos; Andrade,Antero S.R.; Antunes,Carlos Maurício F.; Genaro,OdairA population-based cross-sectional study was set up in Sabará country, Southeastern Brazil, to identify asymptomatic human visceral leishmaniasis in an urban area of low disease prevalence. Blood was collected on filter paper (n=1,604 inhabitants) and examined by indirect immunofluorescent test, enzyme-linked immunosorbent assay and immunochromatographic strip test. The prevalence rates of infection ranged from...
Risk factors for Leishmania chagasi infection in an urban area of Minas Gerais ...
Moreno,Elizabeth Castro; Melo,Maria Norma; Genaro,Odair; Lambertucci,José Roberto; Serufo,José Carlos; Andrade,Antero Silva RibeiroIn order to understand the determinants of human infection by Leishmania chagasi in an urban area, a cross-sectional population based study was conducted using molecular and serologic methods to identify infection. Participants were interviewed using a pre-coded questionnaire. Two criteria were tested to identify risk factors: Model 1- including all participants positive in hybridization by Leishmania donovani ...
Leishmaniose visceral no Brasil: quadro atual, desafios e perspectivas
Gontijo,Célia Maria Ferreira; Melo,Maria NormaNo Brasil, a importância da leishmaniose visceral reside não somente na sua alta incidência e ampla distribuição, mas também na possibilidade de assumir formas graves e letais quando associada ao quadro de má nutrição e infecções concomitantes. A crescente urbanização da doença ocorrida nos últimos 20 anos coloca em pauta a discussão das estratégias de controle empregadas. Neste artigo foram analisados os princ...
Identification and purification of immunogenic proteins from nonliving promasti...
Cardoso,Sandra Regina Afonso; Silva,João Carlos França da; Costa,Roberto Teodoro da; Mayrink,Wilson; Melo,Maria Norma; Michalick,Marilene Suzan MarquesImmunogenic proteins from nonliving promastigote polyvalent Leishmania vaccine against American tegumentary leishmaniasis (Leishvacin®), produced by Biobrás (Biochemistry of Brazil ), Montes Claros, State of Minas Gerais, Brazil, were identified and purified by polyacrylamide electrophoresis gel and electroelution. C57BL/10 mice were vaccinated with proteins with estimated molecular weights of 42, 46, 63, 66, 7...