13 documents found, page 1 of 2
Isolation of Rasamsonia argillacea species complex in a Cystic Fibrosis Adult P...
Carvalho, Dinah; Sabino, Raquel; Veríssimo, Cristina; Simões, Helena; Azevedo, Pilar; Marques Lito, Luis; Melo Cristino, JoséObjectives: Cystic fibrosis (CF) is the most common monogenetic autosomal reces sive disease in the human population. An important fungal biota has been described in respiratory secretions of patients suffering from CF being Aspergillus fumigatus and Candida albicans the most common fungi found. We report the isolation, for the first time in Portugal, of the emerging fungal pathogen Rasamsonia argillacea specie...
Subcutaneous phaeohyphomycosis due to Phaeoacremonium parasiticum in a patient ...
Carvalho, Dinah; Sabino, Raquel; Veríssimo, Cristina; Simões, Helena; Lopes Silva, Susana; Marques, Tiago; Janeiro, João; Marques Lito, LuisObjectives: Phaeoacremonium parasiticum is a ubiquitous dematiaceous mold that rarely causes infection in humans. Its spectrum of disease ranges from subcutaneous infections to disseminated disease. The majority of those reported few cases involve immunocompromised patients. Chronic granulomatous disease (CGD) is an inherited disorder affecting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex...
Klebsiella pneumoniae and Colistin Susceptibility Testing: Performance Evaluati...
Elias, Rita; Melo Cristino, José; Lito, Luís; Pinto, Margarida; Gonçalves, Luísa; Campino, Susana; Clark, Taane; Duarte, Aida; Perdigão, JoãoThe emergence of multidrug resistant Gram-negative pathogens, particularly carbapenemase producers, has forced clinicians to use last line antibiotics, such as colistin. Since colistin susceptibility testing presents several challenges, this study aimed at evaluating the performance of two alternative susceptibility methods for Klebsiella pneumoniae, namely, agar dilution (AD) and MIC test strips (MTS). These a...
Pediatric invasive Pneumococcal disease three years after PCV13 introduction in...
Silva-Costa, Catarina; Silva, Joana; Prados, Lúcia; Ramirez, Mário; Melo Cristino, JoséThe introduction of pneumococcal conjugate vaccines PCV7 and PCV13 led to decreases in incidence of pediatric invasive pneumococcal disease (pIPD) and changes in serotype distribution. We evaluated the consequences of higher vaccine uptake after the introduction of PCV13 in the National Immunization Plan (NIP) in 2015. Besides culture and conventional serotyping, the use of molecular methods to detect and serot...
Dominance of vaccine serotypes in pediatric invasive pneumococcal infections in...
Silva-Costa, Catarina; Brito, Maria J.; Aguiar, Sandra I.; Lopes, Joana P.; Ramirez, Mário; Melo Cristino, JoséWe evaluated the impact of continued 13-valent pneumococcal conjugate vaccine (PCV13) use in the private market (uptake of 61%) in pediatric invasive pneumococcal disease (pIPD) in Portugal (2012-2015). The most frequently detected serotypes were: 3 (n = 32, 13.8%), 14 (n = 23, 9.9%), 1 (n = 23, 9.9%), 7F (n = 15, 6.4%), 19A (n = 13, 5.6%), 6B and 15B/C (both n = 12, 5.2%), and 24F, 10A and 12B (all with n = 10...
Streptococcus agalactiae causing neonatal infections in Portugal 2005-2015: div...
Martins, Elisabete R.; Pedroso-Roussado, Cristiano; Melo Cristino, José; Ramirez, MárioThe molecular characterization of 218 GBS isolates recovered from neonatal invasive infections in Portugal in 2005-2015 revealed the existence of a small number of genetically distinct lineages that were present over a significant time-span. Serotypes III and Ia were dominant in the population, together accounting for >80% of the isolates. Clonal complex 17 included 50% of all isolates, highlighting the importa...
Influenza severe cases in hospitals, between 2014 and 2016 in Portugal
Guiomar, Raquel; Pechirra, Pedro; Cristóvão, Paula; Costa, Inês; Conde, Patrícia; Corte-Real, Rita; Branquinho, Paula; Silvestre, Maria JoséBackground: Since 2009, the Portuguese Laboratory Network (PLNID) for Influenza Diagnosis has integrated 15 Laboratories in mainland and Atlantic Islands of Azores and Madeira. This PLNID added an important contribute to the National Influenza Surveillance Program regarding severe and hospitalized influenza cases. The present study aims to describe influenza viruses detected in influenza like illness (ILI) case...
Persistence of a single clone of Streptococcus agalactiae causing disease in ti...
Barato, P.; Martins, Elisabete R.; Melo Cristino, José; Iregui, C. A.; Ramirez, MárioStreptococcosis is a disease with major health and economic impacts on the tilapia industry worldwide (Mian et al. 2009). In 1997, more than US$150 million of annual losses representing treatment, morbidity and mortality were recorded and this value increased to US$250 million by 2008 (Klesius, Shoemaker & Evans 2008). In Colombia, Streptococcus agalactiae (Lancefield group B streptococci; GBS) is the main bact...
Rede Portuguesa de Laboratórios para o Diagnóstico da Gripe: inverno 2013/2014
Guiomar, Raquel; Pechirra, Pedro; Conde, Patrícia; Cristóvão, Paula; Maia, Ana Carina; Silvestre, Maria José; Almeida Santos, MadalenaA Rede Portuguesa de Laboratórios para o Diagnóstico da Gripe (RPLDG) integra, atualmente, 15 laboratórios maioritariamente hospitalares e é coordenada pelo Laboratório Nacional de Referência para o Vírus da Gripe (LNRVG) do Departamento de Doenças Infecciosas do Instituto Nacional de Saúde Doutor Ricardo Jorge, I.P. A RPLDG realiza o diagnóstico laboratorial do vírus da gripe assim como de outros vírus respira...
Non-invasive Pneumococcal pneumonia in Portugal : serotype distribution and ant...
Horácio, Andreia; Lopes, Joana P.; Ramirez, Mário; Melo Cristino, JoséThere is limited information on the serotypes causing non-invasive pneumococcal pneumonia (NIPP). Our aim was to characterize pneumococci causing NIPP in adults to determine recent changes in serotype prevalence, the potential coverage of pneumococcal vaccines and changes in antimicrobial resistance. Serotypes and antimicrobial susceptibility profiles of a sample of 1300 isolates recovered from adult patients (...