Introduction: Severe asthma affects approximately 4%-5% of asthmatic patients and increases susceptibility to respiratory infections, including SARS-CoV-2. The impact of COVID-19 on severe asthma remains unclear. We aimed to evaluate the effects of SARS-CoV-2 infection on asthma control, quality of life, and lung function.Methods: A retrospective study of 114 severe asthma patients followed in our severe asthma...
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The forced vital capacity (FVC) is a reference measure for respiratory support and phonatory production. Objectives: 1) To obtain FVC data of the Portuguese population and 2) To propose a multiple linear regression model to predict the FVC for clinical practice. Methods: 195 subjects participated (97 men with 10-53 years old and 98 women with 11-50 years old). Weight, height and smoking habits were obtained. FV...
Introduction: Add-on biological monoclonal antibodies such as benralizumab (anti-IL-5Ra) are recommended by international guidelines to reduce exacerbations in severe eosinophilic asthma (SEA). However, few studies have assessed the impact of these therapies on lung function-related outcomes. Our goal was to evaluate the effectiveness of benralizumab on lung function, including lung volumes and airway resistanc...
This paper describes a new information system developed as part of the Portuguese R&D project DECIdE. The project aimed at the development of a platform for infrastructure asset management tailored to Portuguese water utilities. The platform allows the integration of different data from several information systems of the water utilities and includes several tools for the performance assessment of the water supp...
Background and objective Patients with neurogenic bladder (NB) are at a higher risk of developing chronic kidney disease (CKD). Due to their lower muscle mass, the estimated glomerular filtration rate (eGFR) based on creatinine (Cr) may be overestimated and delay the diagnosis of renal failure. This study compared eGFR calculated with different equations based on Cr and/or cystatin C (CysC) in children with NB,...
Recent global and regional assessments of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) show that Nature’s Contributions to People (NCP) are under an alarming threat due to the continuing loss of biodiversity. These assessments call for increasing conservation efforts and a more sustainable use of biodiversity to enhance the chances of halting biodiversity loss and...