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Early detection and personalized treatment in oral cancer: the impact of omics ...

Ribeiro, IP; Barroso, L; Marques, F; Melo, JB; Carreira, IM

BACKGROUND: Oral cancer is one of the most common malignant lesions of the head and neck. This cancer is an aggressive and lethal disease with no significant improvements in the overall survival in the last decades. Moreover, the incidence of oral HPV-positive tumors is rising, especially in young people. This oral neoplasm develops through numerous molecular imbalances that affect key genes and signaling pathw...


Cervical abscess in an immunocompetent patient with Mycobacterium malmoense pul...

Duarte, JN; Marques, N; Barroso, L; Ramos, I; Sá, R; Sanz, D; Ferreira, A; Saraiva da Cunha, JG

BACKGROUND: Mycobacterium malmoense is a nontuberculous mycobacteria seen mainly in two age groups and with different clinical presentations. Most patients are male adults presenting clinical symptoms and signs similar to those of pulmonary tuberculosis. The second group is formed by immunocompetent children with localized cervical lymphadenitis. Although cervical adenitis is the main extrapulmonary manifestati...


Progressive myositis ossificans. Stone man.

Fonseca, J E; Evangelista, T; Barroso, L; Reis, J; Gomes, A R

Myositis ossificans progressiva (MOP) is a rare hereditary connective tissue disease, genetically inherited as an autossomal dominant trait with complete penetrance but variable expression. The onset usually takes place during childhood and progressive involvement of the spinal cord and proximal extremities leads to immobilization and articular dysfunction. We present a case of a 29-year-old woman with the typi...

Date: 2001   |   Origin: Acta Médica Portuguesa

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