Introduction: Immune checkpoint inhibitors (IC) are a new therapeutic option for non-small cell lung cancer. A higher neutrophil/lymphocyte ratio has been associated with worse outcomes in patients treated with immune checkpoint inhibitors, lung cancer included. Aim: Study the relation between value of neutrophil/lymphocyte ratio at day one (D1) and day 30 (D30) of treatment, and overall survival (OS) and progr...
Relatório intercalar do projecto ASSIM - Activating Service-Sharing at InterMunicipal Scale, uma parceria do CEACT/UAL com o CICS.Nova e a CIMT - Comunidade Intermunicipal do Médio Tejo.
The main goal of FUTURAR Project is to estimate the air pollution impact, costs and benefits of emission reduction scenarios for 2030, using modelling tools to estimate the spatial distribution of environment and health impacts over Portugal. This research will support strategies on air pollution mitigation allowing to fill knowledge gaps and adjust/tune/improve estimates of emissions reduction and consequently...
Background: Population health is influenced by interactions between environmental determinants, which are captured by dimensions and indicators. This study aims to systematically review key environmental determinants and respective dimensions and indicators, relevant to evaluate population health in urban settings, and to understand their potential implications into policies. Methods: A search of literature pub...
Background: Population health is influenced by interactions between environmental determinants, which are captured by dimensions and indicators. This study aims to systematically review key environmental determinants and respective dimensions and indicators, relevant to evaluate population health in urban settings, and to understand their potential implications into policies. Methods: A search of literature pub...
The reasons for the high rates of comorbidity between Bipolar (BD) and Borderline Personality (BPD) disorders remain elusive, due to the vast array of shared clinical features, which makes the differential diagnosis difficult. This constitutes an obstacle to provide quality of care services, which results in detrimental effects on individual’s mental health. The analysis of the complex network of connections be...
The mean age of the European population is rising and percentage of adults aged 65 years and older is projected to increase from 16% in 2000 to 20% in 2020. It has been estimated that older subjects spend approximately 19 to 20 h/day indoors. Older individuals may be particularly at risk for detrimental effects from pollutants, even at low concentrations, due to reduced immunological defenses and multiple under...
Few studies have assessed the quality of life (QOL) related to chronic respiratory diseases in the elderly. In the framework of the geriatric study on the health effects of air quality in elderly care centers (GERIA) study, a questionnaire was completed by elderly subjects from 53 selected nursing homes. It included various sections in order to assess respiratory complaints, QOL (World Health Organization QOL (...
Poor ventilation at day care centres (DCCs) was already reported, although its effects on attending children are not clear. This study aimed to evaluate the association between wheezing in children and indoor CO2 (a ventilation surrogate marker) in DCC and to identify behaviours and building characteristics potentially related to CO2. In phase I, 45 DCCs from Lisbon and Oporto (Portugal) were selected through a...