13 documents found, page 1 of 2
Como Retomar a Atividade Cirúrgica Eletiva em Ortopedia Durante a Pandemia COVI...
Diogo, N; Miranda, A; Ruano, A; Mendes, E; Mendes, F; Montes, J; Alves, J; Rosa, I; Alegrete, N; Neves, N; Lourenço, P; Felicíssimo, P; Sá Cardoso, PEste documento foi elaborado pelo Colégio de Ortopedia da Ordem dos Médicos com o objetivo de estabelecer as orientações sobre a retoma da atividade cirúrgica programada em Ortopedia durante a pandemia COVID-19. As presentes normas de orientação: a) definem os critérios que permitem a priorização das cirurgias de acordo com a gravidade da situação clínica, com base em classificações existentes e publicadas; b) ...
How to resume elective orthopaedic surgical procedures during the COVID-19 pand...
Diogo, N; Miranda, A; Ruano, A; Mendes, E; Mendes, F; Montes, J; Alves, J; Rosa, I; Alegrete, N; Neves, N; Lourenço, P; Felicíssimo, P; Sá Cardoso, PThis document was prepared by the College of Orthopedics of the Portuguese Medical Association with the aim of developing the guidelines on the resumption of elective surgical activity in Orthopedics during the COVID-19 pandemic. It sets the criteria that allow the prioritization of surgeries according to the severity of the clinical situation, based on existing and published classifications. Moreover, it provi...
Bioaccessibility of polybrominated diphenyl ethers and their methoxylated metab...
Cruz, R; Mendes, E; Maulvault, AL; Marques, A; Casal, S; Cunha, SCPolybrominated diphenyl ethers (PBDEs) comprise a major class of brominated flame retardants and are well-known endocrine disruptors. The dietary route, through contaminated seafood consumption, is a main contributor to human exposure. Hence, the aim of this work was to provide thorough information on the dietary pathway of PBDEs and their methoxylated metabolites (MeO-PBDEs) after consumption of contaminated c...
Commercial squids: Characterization, assessment of potential health benefits/ri...
Torrinha, A; Gomes, F; Oliveira, M; Cruz, R; Mendes, E; Delerue Matos, C; Casal, S; Motais, SThe most consumed squid species worldwide were characterized regarding their concentrations of minerals, fatty acids, cholesterol and vitamin E. Interspecific comparisons were assessed among species and geographical origin. The health benefits derived from squid consumption were assessed based on daily minerals intake and on nutritional lipid quality indexes. Squids contribute significantly to daily intake of s...
Prodrug design with novel and selective activation mechanisms to improve drug d...
Mendes, E; Gameiro, AP; Perry, MJ; Moreira, R
Synthesis and Biological Assessment of Furoquinolines, Pyrroloquinolines and An...
Martins, C; Carreiras, MC; Mendes, E; de los Rios, C; Léon, R; Ramsay, R; Marco-Contelles, J
Alkylating Agents
Francisco, AP; Perry, MJ; Moreira, R; Mendes, E
Medicinal Chemistry
Moreira, R; Carreiras, MC; Lopes, F; Rocha, MJP; Mendes, E; LConstantino, Dias,; Santos, MM; Lavrado, J; Capela, R; Santana, AB; Valente, E
Evaluation of triazene prodrugs as candidates for melanocyte-directed enzyme pr...
Perry, MJ; Simplício, AL; Coelho, A; Francisco, AP; Oliveira, I; Costa, I; Iley, J; Moreira, R; Mendes, E
Synthesis, stability and in vitro dermal evaluation of aminocarbonyloxymethyl e...
Mendes, E; Furtado, T; Neres, J; Iley, J; Jarvinen, T; Rautio, J; Moreira, RAminocarbonyloxymethyl esters 3 based on (S)-amino acid carriers were synthesised and evaluated as potential prodrugs of carboxylic acid agents. In addition, the compounds were evaluated as topical prodrugs with the aim of improving the dermal delivery of two non-steroidal anti-inflammatory agents: naproxen and flufenamic acid. The lipophilicities of these compounds were determined and their hydrolyses in aqueo...