Introduction and Aim: The timing of anterior fontanelle (AF) closure may be a useful marker for early disease detection. However, the few published studies on this topic have reported significant differences in the normal age ranges of AF closure between countries. The aim of this study was to report AF closure time in the Portuguese population during the last two decades. Methods: This was a 21-year retrospect...
Uterine niche is a recess located in the anterior wall of the uterine isthmus, over the cesarean section scar. This condition is often asymptomatic, but it can be associated with symptoms such as abnormal uterine bleeding, pelvic pain and secondary infertility. Endovaginal ultrasound is the first-line diagnostic method. Treatment includes hormonal methods or surgery, and surgical treatment seems to be the most ...
Introduction and Aim: The timing of anterior fontanelle (AF) closure may be a useful marker for early disease detection. However, the few published studies on this topic have reported significant differences in the normal age ranges of AF closure between countries. The aim of this study was to report AF closure time in the Portuguese population during the last two decades.Methods: This was a 21-year retrospecti...
Introduction: Obesity is one of the most prevalent chronic diseases in childhood, being an important public health issue. Excessive weight has been associated with autonomic dysfunction but the evidence in children is scarce. Therefore, the aim of this study was to assess the effect of overweight and obesity on the autonomic nervous system activity, in children.Material and Methods: Data from a cross-sectional ...
Surfaces with antimicrobial properties are gaining notoriety as an efficient method to avoid surface contamination. Self-disinfecting paints are a promising strategy towards cleaner indoor environments by preventing the colonization of walls with microorganisms. However, its widespread use needs an appropriate toxicological safety evaluation due to the potential for biological disturbance associated to its bioc...
Introduction: The family doctor is often the first contact with the health system and must assess the need for referral to secondary health care (SHC). The objective of this study was to evaluate the satisfaction of general practitioners regarding the articulation with SHC. Material and Methods: Multicenter, longitudinal study. Participants: general practitioners. Data was collected by completing a questionnair...
Knowledge of the beneficial effects of perinatal derivatives (PnD) in wound healing goes back to the early 1900s when the human fetal amniotic membrane served as a biological dressing to treat burns and skin ulcerations. Since the twenty-first century, isolated cells from perinatal tissues and their secretomes have gained increasing scientific interest, as they can be obtained non-invasively, have anti-inflamma...
Wound care has been clinically demanding due to inefficacious treatment that represents an economic burden for healthcare systems. In Europe, approximately 7 million people are diagnosed with untreated wounds, leading to a cost between 6.000€ and 10.000€ per patient/year. In the United States of America, 1.5 million people over 65 years old suffer from chronic wounds. A promising therapeutic strategy is the use...
Children are in contact with local environments, which may affect respiratory symptoms and allergic sensitization. We aimed to assess the effect of the environment and the walkability surrounding schools on lung function, airway inflammation and autonomic nervous system activity. Data on 701 children from 20 primary schools were analysed. Lung function, airway inflammation and pH from exhaled breath condensate ...