40 documents found, page 1 of 4
Estudo sobre a origem do enrugamento do miolo da noz
Farinha, D.; Mendes, M.; Barroso, J.M.; Peixe, A.; Dias, A.; Rato, A.E.The Walnut tree (Juglans regia L.) is one of the most consumed nut species that has been gaining importance with the implementation of new orchards from north to south of the country. The incomplete formation of the seed (Kernel Shrivel) is one of the problems that most depreciates the quality and for which there isn’t an effective control due to its unknown origin. The accumulation of seed reserves that result...
Preliminary findings from the follow-up of pregnant sickle cell disease patient...
Brito, Miguel; Ginete, Catarina; Ferreira, J.; Delgadinho, Mariana; Sebastião, Cruz; Mateus, A.; Mendes, M.; Quinto, F.; Simão, F.; Fernandes, F.Background: In Angola, the prevalence of Sickle Cell Disease (SCD) is almost 2%, and the carriers reach 21% of the population. Although its presentation tends to be very heterogeneous, chronic hemolytic anemia, frequent painful crises, and extensive organ damage are common features of these patients. Pregnancy in SCD patients is associated with an increase in severe outcomes, namely, a high risk of eclampsia an...
Effects of Carica papaya leaf extracts in transcriptional regulation of fetal h...
Mendes, M.; Canteiro, Beatriz; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; Ribeiro, Edna; Brito, Miguel; Gomes, Anita Q.Purpose: Sickle cell disease (SCD) is one of the most common human genetic disorders, which is caused by a single point mutation (Glu6Val) on the HBB gene. Currently, one of the treatments for this global health problem involves the induction of fetal hemoglobin (HbF). There are some drugs on the market that pharmacologically induce HbF, namely Hydroxyurea (HU), however, their safety concerns and the expensive ...
Effects of quercetin in transcriptional regulation of fetal hemoglobin
Canteiro, B.; Mendes, M.; Delgadinho, Mariana; Oliveira, K.; Ginete, Catarina; Gomes, M.; Brito, Miguel; Gomes, Anita Q.; Ribeiro, EdnaPurpose: Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and transport of red blood cells (RBCs) in blood vessels, leading to various clinical complications. The pharmacological reactivation of Fetal Hemoglobin (HbF) is considered to be a viable therapeutic method in SCD. In this regard, hydroxyurea (HU), a powerful ribonucleotide reductase inhibitor, is being employed as a HbF-indu...
Genetic variability and disease severity in a cohort of Angolan sickle cell dis...
Brito, Miguel; Ferreira, J.; Capriello, I.; Ginete, Catarina; Delgadinho, Mariana; Sebastião, Cruz; Mendes, M.; Quinto, F.; Mavunza, F.; Vasconcelos, J.Purpose: Sickle Cell Anaemia (SCA) is an inherited autosomal and lethal blood disorder caused by a mutation in the HBB gene that promotes haemoglobin (Hb) polymerization and consequent sickling of red blood cells (RBCs) in hypoxia. Regardless of being a monogenic disease, SCA has a remarkably high clinical heterogeneity in its phenotypic expression. Several factors have been shown to modulate the clinical manif...
Cut-off points of the 1-minute sit-to-stand test to detect functional impairmen...
Dias, C.; Machado, A.; Mendes, M.; Ferreira, D.; Martins, V.; Simão, P.; Marques, A.Introduction: Functional status is a key outcome in people with chronic obstructive pulmonary disease (COPD) and can be defined as an individual’s ability to perform normal daily activities required to meet basic needs, fulfill usual roles, and maintain health and well-being. The 1-minute sit-to-stand test (1-min STS) is a wellestablished measure to assess functional status in people with COPD that can be used ...
The Late Permian in the Muarádzi Sub-basin, Moatize-Minjova Basin, Mozambique –...
Lopes, Gilda; Pereira, Z.; Fernandes, Paulo; Mendes, M.; Marques, J.; Jorge, R.C.G.S.A study involving lithofacies, palynofacies, and palynological analysis is presented for the Muarádzi Sub-basin. This sub-basin is part of the Moatize-Minjova Basin (MMB), a crucial Karoo aged coalfield in Mozambique previously situated in the southern-central part of Gondwana.
Preliminary late Miocene palynomorph assemblages from the Quifangondo and Luand...
Rodrigues, C. F.; Pereira, Z.; Mendes, M.; Nsungani, P. C.; Fernandes, P.; Lopes, Gilda; Duarte, L., V; Aboelkomsan, W.; Taylor, E.; Tyrrell, M.A Miocene succession exposed at the Cabo Ledo and Miradouro da Lua sections in the Onshore Kwanza Basin, Angola, was examined for palynology. Palynomorphs of preliminary late Miocene age identified are presented herein. The upper part of the Quifangondo Formation is dated as middle Tortonian in age based on the co-occurrence of the pollen grain Fenestrites spinosus and the dinoflagellate species Selenopemphix a...
A journey towards lean: The case of a small and medium-sized enterprise (SME)
Pimentel, L.; Mendes, M.Objectives: The objective of this paper is to examine whether it is feasible to implement Lean in a small and medium-sized enterprise (SME), although literature mentions that it is uncommon and unlikely. Additionally, this paper explores how Lean has been progressively applied to a single SME, if there is room for improvement and how it can be accomplished. Finally, this paper seeks to understand if Lean can be...
Vive Côa
Amado, Jorge; Ribeiro, Inês; Santos, Luana; Villares, Tadeu; Barroso, Bárbara; Barbedo, Inês; Navarro, B.; Aubry, T.; Batarda, A.; Mendes, M.Numa estratégia de inovação formativa, renovação pedagógica e cooperação com as instituições da região, o IPB tem estabelecido parcerias diversas. No âmbito da inovação formativa surgiram unidades curriculares diferenciadas, como o Project Y. Num ambiente de estúdio, típico das indústrias criativas, são desenvolvidos projetos em parceria com a comunidade (empresas e instituições). Trata-se de um contexto de tra...