5 documents found, page 1 of 1
First molecular identification of fasciola gigantica in slaughtered cattle in c...
Levy, Sara; Calado, Manuela; Mateus, Teresa Letra; Vieira-Pinto, MadalenaA study on fasciolosis prevalence, gross pathological lesions, fluke genetic identification and coprological analysis was carried out in slaughtered cattle from one abattoir in Cape Verde. Of the 131 cattle inspected over two months, 12 (9.0%) presented fasciolosis-compatible lesions (FCL) that resulted in liver condemnation. The genetic characterization of the flukes collected, through restriction fragment len...
Genetic analysis of Schistosoma mansoni sensitive and resistant strains to praz...
Mendes, Tiago; Calado, Manuela; Clemente, Isabel; Belo, Silvana; Afonso, AnaPraziquantel (PZQ) is the drug of choice in the treatment of schistosomiasis due to its high cure rates and no significant side effects. Currently, more and more cases of resistance or increased tolerance to PZQ have been reported, consequently, there were recommendations for continuous monitoring of drug resistance. In our laboratory, we selected a parasitic line of Schistosoma mansoni, through constant drug p...
Apparent dominance of the G1-G3 genetic cluster of echinococcus granulosus stra...
Beato, Sílvia; Parreira, Ricardo; Calado, Manuela; Grácio, Maria AméliaInfection by the larval stage of the cestode Echinococcus granulosus causes a disease known as cystic echinococcosis or hydatidosis, which is one of the most widespread zoonotic infections of veterinary and medical importance. Numerous studies have shown that E. granulosus exists as a complex of strains differing in a wide variety of criteria. Ten distinct genotypes (G1-G10) have been identified with potential ...
PCR-RFLP e genotipagem de echinococcus granulosus
Beato, Sílvia; Calado, Manuela; Clemente, Isabel; Grácio, Maria AméliaA hidatidose é uma zoonose, causada pelo helminta Echinococcus granulosus, presente de um modo geral, em todo o globo terrestre tendo na região mediterrânica uma elevada importância. Estão descritos, para esta espécie, 10 genótipos (G1 a G10) em saúde pública ligados a diferentes hospedeiros intermediários. Das técnicas de biologia molecular utilizadas para a genotipagem do E. granulosus, umas mostraram-se mais...
Hydatidosis in Portugal: a mitochondrial phylogeny approach
Beato, Sílvia; Calado, Manuela; Parreira, Ricardo; Grácio, Maria AméliaHydatidosis is a worldwide zoonosis caused by the larval stage of the tapeworm Echinococcus granulosus. The taxonomy and phylogeny of the genus Echinococcus has been a controversial issue for several years but with the usage of molecular tools to characterize the etiological agents these aspects had been clarified and a new classification has been proposed and is now widely accepted. The aim of this work is to ...