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Estimating Attractor Reachability in Asynchronous Logical Models
Mendes, Nuno D.; Henriques, Rui; Remy, Elisabeth; Carneiro, Jorge; Monteiro, Pedro T.; Chaouiya, ClaudineLogical models are well-suited to capture salient dynamical properties of regulatory networks. For networks controlling cell fate decisions, cell fates are associated with model attractors (stable states or cyclic attractors) whose identification and reachability properties are particularly relevant. While synchronous updates assume unlikely instantaneous or identical rates associated with component changes, th...
Date: 2018
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Origin: ARCA - Access to Research and Communication Annals