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Root causes and outcomes of postoperative pulmonary complications after abdomin...

Fernandes, A; Rodrigues, J; Lages, P; Lanca, S; Mendes, P; Antunes, L; Santos, CS; Castro, C; Costa, RS; Lopes, CS; da Costa, PM; Santos, LL

Background: Postoperative pulmonary complications (PPCs) contribute significantly to overall postoperative morbidity and mortality. In abdominal surgery, PPCs remain frequent. The study aimed to analyze the profile and outcomes of PPCs in patients submitted to abdominal surgery and admitted in a Portuguese polyvalent intensive care unit. Methods: From January to December 2017 in the polyvalent intensive care un...


Functional Study of DAND5 Variant in Patients with Congenital Heart Disease and...

Cristo, F; Inácio, JM; Almeida, S; Mendes, P; Martins, DS; Maio, J; Anjos, R; Belo, JA

Perturbations on the Left-Right axis establishment lead to laterality defects, with frequently associated Congenital Heart Diseases (CHDs). Indeed, in the last decade, it has been reported that the etiology of isolated cases of CHDs or cases of laterality defects with associated CHDs is linked with variants of genes involved in the Nodal signaling pathway.


One-shot diagnostic and prognostic assessment in intermediate- to high-risk acu...

Baptista, R; Santiago, I; Jorge, E; Teixeira, R; Mendes, P; Curvo-Semedo, L; Castro, G; Monteiro, P; Caseiro-Alves, F; Providência, LA

INTRODUCTION: Contrast-enhanced multidetector computed tomography (MDCT) is useful for the diagnosis of pulmonary embolism (PE). However, current guidelines do not support its use for risk assessment in acute PE patients. OBJECTIVES: We compared the prognostic impact of MDCT-derived indices regarding medium-term mortality in a population of intermediate- to high-risk PE patients, mostly treated by thrombolysis....


Novas Estratégias de Prevenção da Tosse Convulsa

D´Elia, C; Mendes, P; Casimiro, A

Introdução: Nos últimos 30 anos, em vários países, tem sido relatado um aumento da incidência de tosse convulsa, sobretudo em adolescentes e adultos, apesar das altas taxas de cobertura de imunização primária. Objectivos: Rever aspectos da epidemiologia da tosse convulsa, descrever algumas estratégias de controlo, com ênfase nas que incluem a utilização de vacinas com menores quantidades do toxóide diftérico e ...


Left ventricular end diastolic pressure and acute coronary syndromes

Teixeira, R; Lourenço, C; Baptista, R; Jorge, E; Mendes, P; Saraiva, F; Monteiro, S; Monteiro, P; Ferreira, MJ; Freitas, M; Providência, LA

BACKGROUND: Data is lacking in the literature regarding the prognostic impact of left ventricular-end diastolic pressure (LVEDP) across acute coronary syndromes (ACS). OBJECTIVE: To assess LVEDP and its prognostic implications in ACS patients. METHODS: Prospective, longitudinal and continuous study of 1329 ACS patients from a single center between 2004 and 2006. Diastolic function was determined by LVEDP. Popul...


Can we improve outcomes in patients with previous coronary artery bypass surger...

Teixeira, R; Lourenço, C; António, N; Jorge, E; Baptista, R; Saraiva, F; Mendes, P; Monteiro, S; Gonçalves, F; Monteiro, P; Freitas, M; Providência, LA

INTRODUCTION AND OBJECTIVES: Prognosis and in-hospital management of patients with acute coronary syndrome (ACS) and a history of coronary artery bypass graft (CABG) surgery are still debated. The objective of this study was to characterize ACS patients with a CABG and to compare their in-hospital and postdischarge outcomes with those of patients without a CABG. METHODS: This ongoing prospective observational s...


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