9 documents found, page 1 of 1
Antifungal activity of liriodenine on clinical strains of Cryptococcus neoforma...
Levorato-Vinche,Adriele Dandara; Melhem,Marcia de Souza Carvalho; Bonfietti,Lucas Xavier; de-la-Cruz-Chacón,Iván; Boaro,Carmen Sílvia FernandesAbstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and AmB demands hospitalization. The combination of AmB with the fungistatic fluconazole (FLC) or the use of high FLC dai...
Impact of laryngeal sequelae on voice- and swallowing-related outcomes in parac...
Pissurno,Neisa Santos Carvalho Alves; Esteves,Lucas da Motta; Benedito,Juliana Marques; Giglio,Vanessa Ponsano; Carvalho,Lídia Raquel deAbstract Background: The present study was carried out aiming to evaluate the impact of laryngeal sequelae on the quality of life of treated paracoccidioidomycosis (PCM) patients. Methods: This cross-sectional study was conducted at the Otorhinolaryngology Outpatient Clinic of the University Hospital, Federal University of Mato Grosso do Sul, Brazil. Thirty-two PCM patients considered clinically and immunologic...
Antifungal activity of liriodenine on agents of systemic mycoses, with emphasis...
Vinche,Adriele Dandara Levorato; de- la-Cruz-Chacón,Iván; González-Esquinca,Alma Rosa; Silva,Julhiany de Fátima da; Ferreira,GiselaAbstract Background: Endemic systemic mycoses remain a health challenge, since these opportunistic diseases are increasingly infecting immunosuppressed patients. The simultaneous use of antifungal compounds and other drugs to treat infectious or non-infectious diseases has led to several interactions and undesirable effects. Thus, new antifungal compounds should be investigated. The present study aimed to evalu...
Treatment compliance of patients with paracoccidioidomycosis in Central-West Br...
Andrade,Ursulla Vilella; Oliveira,Sandra Maria do Valle Leone de; Chang,Marilene Rodrigues; Pereira,Edy Firmina; Marques,Ana Paula da CostaABSTRACT Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis. Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. In order to be considered compliant, patients needed to present two established criteria: (1) receive medicines from ...
Standardization and validation of Dot-ELISA assay for Paracoccidioides brasilie...
Kamikawa,Camila Mika; Mendes,Rinaldo Poncio; Vicentini,Adriana PardiniAbstract Background Paracoccidioidomycosis (PCM) is a neglected systemic mycosis caused by a dimorphic fungus of the Paracoccidioides genus. The standard diagnosis is based on isolation of the fungi in culture, and by microscopic visualization of characteristic multiple budding yeast cells in biological samples. However, in some situations, access to the site of injury prevents the collection of biological mate...
Africanized honeybee stings: how to treat them
Almeida,Ricardo Augusto Monteiro de Barros; Olivo,Taylor Endrigo Toscano; Mendes,Rinaldo Poncio; Barraviera,Silvia Regina Catharino SartoriINTRODUCTION: In 1956, Africanized honeybees (AHB) migrated from Brazil to other regions of the Western Hemisphere, including South, Central, and North America, except for Canada. Despite being productive, they are highly aggressive and cause fatal accidents. This study aimed to evaluate patients at the Clinical Hospital of Botucatu Medical School (HC-FMB) and to propose treatment guidelines. METHODS: From 2005...
Cryptosporidiosis of the biliary tract mimicking pancreatic cancer in an AIDS p...
Souza,Lenice do Rosário de; Rodrigues,Maria Aparecida M.; Morceli,José; Kemp,Raphael; Mendes,Rinaldo PoncioDiarrhea caused by Cryptosporidium sp is frequent in patients with AIDS, but involvement of other organs of the digestive tract is uncommon. We report a case of Cryptosporidium-associated obstruction of the biliary tract mimicking cancer of the head of the pancreas in a 43-year-old woman with AIDS.
Leptospirosis patient with AIDS the first case reported
Neves,Elizabeth de Souza; Pereira,Martha Maria; Galhardo,Maria Clara Gutierrez; Caroli,Adriana; Andrade,Jarbas; Morgado,Mariza GonçalvesA case of renal icterohaemorrhagic leptospirosis involving a patient with acquired immunodeficiency syndrome (AIDS) is reported. Despite the low levels of CD4+ Tlymphocytes, the clinical course of leptospirosis was similar to that observed in non-immunodepressed patients, and no worsening of AIDS occurred due to the infebtion by the spirochete. Serologic conversion was observed in the microscopic agglutination ...
Isoniazid acetylating phenotype in patients with paracoccidioidomycosis and its...
Barraviera,Benedito; Pereira,Paulo Câmara Marques; Machado,Jussara Marcondes; Souza,Maria Julia de; Lima,Carlos Roberto G.; Curi,Paulo RobertoThe authors evaluated the isoniazid acetylating phenotype and measured hematocrit, hemoglobin, glucose-6-phosphate dehydrogenase and glutathione reductase activities plus serum sulfadoxin levels in 39 patients with paracoccidioidomycosis (33 males and 6 females) aged 17 to 58 years. Twenty one (53.84%) of the patients presented a slow acetylatingphenotype and 18(46.16%) a fast acetylating phenotype. Glucose-6-p...