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Effectiveness and safety of first-generation protease inhibitors in real-world ...

Callefi, Luciana Azevedo; Villela-Nogueira, Cristiane Alves; de Barros Tenore, Simone; Carnaúba-Júnior, Dimas; Coelho, Henrique Sérgio Moraes

OBJECTIVE: To evaluate the effectiveness and safety of first-generation protease inhibitors for the treatment of genotype 1 hepatitis C virus-infected patients at Brazilian reference centers. METHODS: This multicenter cross-sectional study included hepatitis C virus genotype 1 monoinfected patients treated with Peg-interferon, ribavirin, and either boceprevir (n=158) or telaprevir (n=557) between July 2013 and ...

Date: 2017   |   Origin: Oasisbr

Clinical laboratory assessment of hepatitis C and HIV coinfected patients accor...

Navarro, Roberto M. Carrasco; Mendes-Correa, Maria Cássia Jacintho; Cavalheiro, Norma de Paula; Barone, Antonio Alci

During the year of 2001, a retrospective, descriptive study in order to determine the influence of the antiretroviral therapy received by 111 HIV-HCV coinfected patients who had undergone at least one liver biopsy was conduced, 74 of them were treated with a protease inhibitor regimen (WPI), and 37 with a non-protease inhibitor regimen (NPI). The main characteristics found were: a young patient population (mean...

Date: 2005   |   Origin: Oasisbr

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