Made available in DSpace on 2022-04-29T08:46:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-28; Center for Information Technology; Center for Scientific Review; National Institutes of Health; Office of Extramural Research, National Institutes of Health; Office of Research Infrastructure Programs, National Institutes of Health; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fu...
Made available in DSpace on 2022-04-29T08:46:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-12-01; National Institute of General Medical Sciences; As whole-genome sequencing (WGS) becomes the gold standard tool for studying population genomics and medical applications, data on diverse non-European and admixed individuals are still scarce. Here, we present a high-coverage WGS dataset of 1,171 highly a...
Made available in DSpace on 2021-06-25T10:53:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); KIR2DL4 is an important immune modulator expressed in natural killer cells; HLA-G is its main ligand. We have characterized the KIR2DL4 genetic diversity by considering the promoter, all exons, and all introns in a highly admixed Brazilian p...
Made available in DSpace on 2021-06-25T11:03:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-01; Institut de Recherche pour le Développement; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: Little attention has been devoted to the role of the immunoregulatory HLA-E/-F/−G genes in malaria. We evalu...
Made available in DSpace on 2020-12-10T19:37:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-09-01; Univ Sao Paulo, FMRP, Ribeirao Preto, Brazil; Univ Paris 05, Sorbonne, IRD, MERIT, Paris, France; Univ Abomey Calavi, Dept Zool, Cotonou, Benin; Sao Paulo State Univ UNESP, Sch Med, Dept Pathol, Botucatu, SP, Brazil; Fac Sci Sante, Ctr Etud & Rech Paludisme Associe Grossesse & Enf, Cotonou, Benin; Univ ...
Made available in DSpace on 2020-12-12T02:19:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Human leukocyte antigen-C (HLA-C) is a classical HLA class I molecule that binds and presents peptides to cytotoxic T lymphocytes in the cell surface. HLA-C has a dual function because it also interacts with Killer-cell immunoglobulin-like receptors (KIR) receptors expressed in natural killer and T cell...
Made available in DSpace on 2019-10-06T16:48:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; HLA-G/E/F genes exhibit immunomodulatory properties and are expressed in placenta. Little attention has been devoted to the study of these genes in sub-Saharan African populations, which are yet the most diverse. To fill this gap, we evaluated the complete gene variability, approximately 5.1 kb for HLA-...
Made available in DSpace on 2019-10-06T15:22:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-02-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); HLA-F is one of the most conserved loci among the HLA gene family. The exact function of HLA-F is stil...
Made available in DSpace on 2018-11-26T17:40:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Univ Sao Paulo, FMRP, Ribeirao Preto, Brazil; Univ Estadual Paulista Unesp, Fac Med Botucatu, Dept Pathol, Botucatu, SP, Brazil; Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Gynecol & Obstet, Ribeirao Preto, Brazil; Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Internal Med, Div Endocrinol, Ribeirao Pret...
Made available in DSpace on 2018-11-26T17:06:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-01-01; Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Clin Med, Ribeirao Preto, Brazil; Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Genet, Ribeirao Preto, Brazil; Univ Sao Paulo, Fac Med Ribeirao Preto, Reg Blood Ctr, Ribeirao Preto, Brazil; UNESP Sao Paulo State Univ, Sch Med, Dept Pathol, Botucatu, SP, Brazil...