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Impact of physical exercise programs in breast cancer survivors on health-relat...

Joaquim, Ana; Leão, Inês; Antunes, Pedro; Capela, Andreia; Viamonte, Sofia; Alves, Alberto J.; Helguero, Luísa A.; Macedo, Ana

Background: Breast cancer is the most common cancer worldwide, and despite remarkable progress in its treatment, the survivors' quality of life is hampered by treatment-related side effects that impair psychosocial and physiological outcomes. Several studies have established the benefits of physical exercise in breast cancer survivors in recent years. Physical exercise reduces the impact of treatment-related ad...


A step-by-step synthesis of triazole-benzimidazole-chalcone hybrids: Anticancer...

Djemoui, Amar; Naouri, Abdelkader; Ouahrani, Mohammed Ridha; Djemoui, Djamila; Lahcene, Souli; Lahrech, Mokhtar Boualem; Boukenna, Leila

Novel series of triazole-benzimidazole-chalcone hybrid compounds have been synthesized via click chemistry, between different azide derivatives and substituted benzimidazole terminal alkynes bearing a chalcone moiety. The starting alkynes are prepared via base-catalysed nitrogen alkylation of pre-synthetized benzimidazole-chalcone substrates. All the intermediates as well as the final products are fully charact...


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