20 documents found, page 1 of 2
Formulation strategies for enhancing growth of akkermansia muciniphila and its ...
Freitas, A.; Almeida, D.; Machado, D.; Mendo, S.; Gomes, A.Gut bacterium Akkermansia muciniphila has been recognized as a new potential probiotic due to promising outcomes in the prevention and treatment of several human diseases. However, despite its multiple beneficial effects, its viability is compromised by the presence of oxygen. This has so far precluded its application namely in the development of nutraceutical/therapeutic formulations. In order to enhance growt...
RIBE at an inter-organismic level: a study on genotoxic effects in Daphnia magn...
Reis, P.; Lourenço, J.; Carvalho, F. P.; Oliveira, J.; Malta, M.; Mendo, S.; Pereira, R.The induction of RIBE (Radiation Induced Bystander Effect) is a non-target effect of low radiation doses that has already been verified at an inter-organismic level in fish and small mammals. Although the theoretical impact in the field of environmental risk assessment (ERA) is possible, there is a gap of knowledge regarding this phenomenon in invertebrate groups and following environmentally relevant exposures...
Presença de bactérias patogénicas e resistência antimicrobiana em ungulados sel...
Dias, D.; Torres, R.; Fonseca, C.; Mendo, S.; Caetano, T.De uma forma geral, os animais selvagens não estão expostos a agentes antimicrobianos. Assim, espera-se que a resistência da sua flora bacteriana a antibacterianos seja muito reduzida. Contudo, a crescente interação destes animais com atividades antropogénicas pode contribuir para um aumento da resistência das suas comunidades bacterianas. O presente estudo teve como objetivo: i) avaliar os níveis de resistênci...
The lanthipeptides of Bacillus methylotrophicus and their association with geno...
Dias, L.; Caetano, T.; Pinheiro, M.; Mendo, S.tBacillus methylotrophicus strains are known for their potential as plant-growth promoters and as micro-bial pesticides that effectively control plant diseases caused by bacteria and fungi. Over the past few years,a wide diversity of their secondary metabolites has been extensively characterized. Among these are theRiPPs lanthipeptides, which are an important and growing group of notable compounds. The increasi...
Toxicity of tributyltin (TBT) to terrestrial organisms and its species sensitiv...
Silva, P.V.; Silva, A.R.R.; Mendo, S.; Loureiro, S.The contamination of the terrestrial environment by disposal of tributyltin (TBT) by contaminated harbour sediments, sewage sludge and/or biocide products has been raising concerns and it may pose a risk to soil invertebrates and plants. This study aimed to improve the amount and quality of data for TBT toxicity in soils in order to assess the ecological risk of TBT to the terrestrial ecosystems. For this, bioa...
Bioengineering of lanthipeptides in Escherichia coli: assessing the specificity...
Caetano, T.; Barbosa, J.; Möesker, E.; Süssmuth, R. D.; Mendo, S.The lichenicidin and haloduracin biosynthetic machinery specificity was investigated invivo in Escherichia coli. Unlike previous reports using different hosts, it was found that the biosynthetic machineries of lichenicidin and haloduracin are highly specific to their dedicated peptide precursors. Likewise, the substitution of lichenicidin structural genes by chimeras of lichenicidin leader sequences and halodur...
Biomonitoring a human population inhabiting nearby a deactivated uranium mine
Lourenço, J.; Pereira, R.; Pinto, F.; Caetano, T.; Silva, A.; Carvalheiro, T.; Guimarães, A.; Gonçalves, F.; Paiva, A.; Mendo, S.Environmental exposure to uranium and its daughter radionuclides, has been linked to several negative effects such as those related with important physiological processes, like hematopoiesis, and may also be associated with genotoxicity effects. Herein, genotoxic effects, immunotoxicity, trace elements and C reactive protein (CRP) analyses, were performed in peripheral blood samples collected from individuals o...
The performance of Fraxinus angustifolia as a helper for metal phytoremediation...
Pinheiro, J. C.; Marques, C. R.; Pinto, G.; Bouguerra, S.; Mendo, S.; Gomes, N. C.; Gonçalves, F.; Rocha-Santos, T.; Duarte, A. C.; Roembke, J.Soil contamination with metals is a serious problem requiring urgent measures to counteract their impacts. The conventional soil remediation techniques are often inefficient and expensive. In this work, we studied the potential of the species Fraxinus angustifolia for the phytoremediation of metal contaminated soils from the Cunha Baixa uranium mine (Mangualde, Portugal). The plants were exposed to a contaminat...
A novel complex class 1 integron found in a Klebsiella pneumoniae isolate from ...
Santos, C.; Caetano, T.; Ferreira, S.; Ramalheira, E.; Mendo, S.Klebsiella pneumoniae Kp1 carrying a novel complex class 1 integron was isolated from an inanimate surface of a female ward sanitary facility in the Hospital Infante D. Pedro, Aveiro, central Portugal. The integron consists of two variable regions (VRs); VR1 was previously described in Escherichia coli and Vibrio cholerae, and VR2 contains an In37-like structure and is located downstream of an ISCR1 element. Th...
Effect of high pressure on microorganism’s growth, antioxidant capacity, and wi...
Santos, M. C.; Rodrigues, A.; Rodrigues, C.; Mendo, S.; Saraiva, J. A.; Nunes, C.; Coimbra, M. A.In this work, the effect of high hydrostatic pressure (HHP) treatment of wine, as substitute of SO2, was evaluated by quantification of microbial load, antioxidant capacity, and colour. For this purpose, red wine of two consecutive harvests (2008 and 2009) was produced without the addition of SO2. At the end of the alcoholic fermentation, the wine was pressurized at 350 MPa for 20 min at 20 ºC. After nine month...