39 documents found, page 1 of 4
Association of Mycobacterium avium paratuberculosis serostatus with age at firs...
Martins, E; Oliveira, P; Correia-Gomes, C; Mendonça, D; Ribeiro, JNMycobacterium avium ssp. paratuberculosis (MAP) is the causative agent of bovine paratuberculosis, also known as Johne's disease. This infection is responsible for negative effects, ranging from reduction of milk production to reproductive compromise and increased susceptibility to other diseases such as mastitis. Contradictory information on the association between this infection and reproductive performance h...
Investigating the Life Expectancy at Birth of Companion Dogs in Portugal Using ...
Geraz, H; Pinello, K; Mendonça, D; Severo, M; Niza-Ribeiro, JThis study aimed to provide a comprehensive picture of the life expectancy of dogs in Portugal, focusing on the impact of diverse factors including breed, sex, size, and skull shape. The final dataset, gathering data from the national registry database, consisted of 278,116 dogs with confirmed deaths. The mean lifespan at birth for all the dogs was around 8.91 years, with the female dogs tended to have a simila...
Epidemiology of Psoriasis in Portugal: A Population-Based Study
Torres, T; Filipe, P; Menezes Brandão, F; Figueiredo, A; Pinto Soares, A; Sousa Basto, A; Rebelo, C; Correia, O; Ferreira, P; Brasileiro, AIntroduction: Psoriasis is a common, chronic, and inflammatory skin disorder with a high personal, social and economic burden and important implica-tions for healthcare systems. The aim of this study was to provide an epidemiological characterization of individuals with psoriasis in Portugal.Material and Methods: A large observational, cross-sectional, nationwide, population-based survey study developed by the ...
One-year mortality after hospitalization for acute heart failure: Predicting fa...
Marques, I; Ramos, RL; Mendonça, D; Teixeira, LIntroduction and objectives: One-year mortality after hospitalization for heart failure (HF) is high. This study aims to identify predictive factors of one-year mortality.Methods: This is a retrospective, single-center and observational study. All patients hospitalized for acute HF during one year were enrolled.Results: A total of 429 patients were enrolled, mean age of 79 years. The in-hospital and one-year al...
Multiple autoimmune syndrome: Clinical, immunological and genotypic characteriz...
Fidalgo, M; Faria, R; Carvalho, C; Carvalheiras, G; Mendonça, D; Farinha, F; da Silva, BM; Vasconcelos, CIntroduction: The existence of subphenotypes common to several autoimmune diseases (AIDs) suggests a shared physiopathology - autoimmune tautology. Multiple Autoimmune Syndrome (MAS) - the coexistence of three or more AIDs in one person-, best illustrates that polyautoimmunity is more than a coincidence. Objectives: Characterize and compare the monoautoimmune and MAS patients. Understand if clustering of AIDs l...
Effects of a nursing care program focused on basic self-care in older acute med...
Rodrigues, C; Mendonça, D; Martins, MMBackground: Acute illness and hospitalization are often associated with decreased independence in basic activities of daily living. The aim of this study was to test the hypothesis that a nursing care program focused on basic self-care (N_BSC) improves functional outcomes in older patients admitted to an acute medical unit. Methods: This was a 2-group randomized controlled trial with repeated measures: 182 olde...
Functional trajectories of older acute medical inpatients
Rodrigues, C; Mendonça, D; Martins, MMObjectives: To describe the changes in basic activities of daily living (BADL) function before and during hospital admission in older patients admitted to an acute medical unit and to assess the effect of age on loss of BADL function. Methods: Prospective observational study. The study included 91 patients aged 65 and older consecutively admitted to an acute medical unit of an urban public teaching hospital in ...
Large Normal Alleles of ATXN2 Decrease Age at Onset in Transthyretin Familial A...
Santos, D; Coelho, T; Alves-Ferreira, M; Sequeiros, J; Mendonça, D; Alonso, I; Sousa, A; Lemos, CObjective: Transthyretin (TTR)-related familial amyloid polyneuropathy (FAP) is an autosomal dominant neurological disease, caused most frequently by a Val30Met (now classified as Val50Met) substitution in TTR. Age at onset (AO) ranges from 19 to 82 years, and variability exists mostly between generations. Unstable oligonucleotide repeats in various genes are the mechanism behind several neurological diseases, ...
Deprivation-specific life tables using multivariable flexible modelling - trend...
Antunes, L; Mendonça, D; Ribeiro, AI; Maringe, C; Rachet, BBackground Completing mortality data by information on possible socioeconomic inequalities in mortality is crucial for policy planning. The aim of this study was to build deprivation-specific life tables using the Portuguese version of the European Deprivation Index (EDI) as a measure of area-level socioeconomic deprivation, and to evaluate mortality trends between the periods 2000–2002 and 2010–2012. Methods S...
Joint modelling of longitudinal and competing risks data in clinical research
Teixeira, L; Sousa, I; Rodrigues, A; Mendonça, DJoint modelling of longitudinal and survival data has received much attention in the recent years and is becoming increasingly used in clinical studies. When the longitudinal outcome and survival endpoints are associated, the many well-established models with different specifications proposed to analyse separately longitudinal and time-to-event outcomes are not suitable to analyse such data and a joint modellin...