2 documents found, page 1 of 1
Genetic information improves the prediction of major adverse cardiovascular eve...
Mendonça,Maria Isabel; Henriques,Eva; Borges,Sofia; Sousa,Ana Célia; Pereira,Andreia; Santos,Marina; Temtem,Margarida; Freitas,Sónia; Monteiro,JoelAbstract The inclusion of a genetic risk score (GRS) can modify the risk prediction of coronary artery disease (CAD), providing an advantage over the use of traditional models. The predictive value of the genetic information on the recurrence of major adverse cardiovascular events (MACE) remains controversial. A total of 33 genetic variants previously associated with CAD were genotyped in 1587 CAD patients from...
Genetic Risk Analysis of Coronary Artery Disease in a Population-based Study in...
Pereira,Andreia; Mendonça,Maria Isabel; Borges,Sofia; Freitas,Sónia; Henriques,Eva; Rodrigues,Mariana; Freitas,Ana Isabel; Sousa,Ana CéliaAbstract Background: Genetic risk score can quantify individual’s predisposition to coronary artery disease; however, its usefulness as an independent risk predictor remains inconclusive. Objective: To evaluate the incremental predictive value of a genetic risk score to traditional risk factors associated with coronary disease. Methods: Thirty-three genetic variants previously associated with coronary disease w...