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Environmental monitoring and biomarkers of exposure to styrene in chemical indu...

Fernandes, Daniela; Meneses, Márcia; Albuquerque, Paula; Barros, Miguel

Biomarkers of exposure to chemicals, such as styrene, allow estimating the exposure to a particular compound by measuring the compound or it(s) metabolite(s) in body fluids. An example is the determination of mandelic acid and phenylglyoxylic acid in urine. Indicators of genotoxicity are categorized as: (a) DNA and protein adducts; (b) DNA strand breaks. Styrene metabolism is initiated by Cytochrome P450 enzyme...

Date: 2022   |   Origin: Saúde & Tecnologia

Target specific post-harvest treatment by gamma radiation for the microbial saf...

Meneses, Márcia; Antonio, Amilcar L.; Cabo Verde, Sandra

This study aimed to assess a specific gamma radiation dose to be applied as a post-harvest process to guarantee the microbial safety of two medicinal plants, Melissa officinalis and Aloysia citrodora. Dried plants treated with gamma radiation indicated that a dose of 5 kGy could be applied as a post-harvest treatment process of M. officinalis and A. citrodora, assuring the microbial safety of dried medicinal pl...


Target specific post-harvest treatment by gamma radiation for the microbial saf...

Meneses, Márcia; Antonio, Amilcar L.; Cabo Verde, Sandra

This study aimed to assess a specific gamma radiation dose to be applied as a post-harvest process to guarantee the microbial safety of two medicinal plants, Melissa officinalis and Aloysia citrodora. Dried plants treated with gamma radiation indicated that a dose of 5 kGy could be applied as a post-harvest treatment process of M. officinalis and A. citrodora, assuring the microbial safety of dried medicinal pl...

Date: 2021   |   Origin: Biblioteca Digital do IPB

The genotoxicity of an organic solvent mixture: a human biomonitoring study and...

Ladeira, Carina; Gajski, Goran; Meneses, Márcia; Gerić, Marko; Viegas, Susana

This study aimed to evaluate occupational exposure to a styrene and xylene mixture through environmental exposure assessment and identify the potential genotoxic effects through biological monitoring. Secondly, we also exposed human peripheral blood cells in vitro to both xylene and styrene either alone or in a mixture at concentrations found in occupational settings in order to understand their mechanism of ac...


Human biomonitoring on co-exposure to styrene and xylene: assessment of genotox...

Ladeira, Carina; Meneses, Márcia; Viegas, Susana

Workplace environment represents the main source of exposure to organic solvents. These solvents are extensively used in the chemical industry and particularly important to various chemical and technical processes. Co-exposure to styrene and xylene frequently occurs in numerous occupational settings. These substances are raw materials applied in processes during the manufacture of polymers, paints, pigments, an...


Occupational co-exposure to solvents: the case of styrene and xylene

Meneses, Márcia; Viegas, Susana

Although the health effects of single contaminants may be apparent under circumstances of high exposure, the great majority of people are exposed to several chemicals simultaneously. Exposure to mixtures or co-exposure to several substances is the common feature in occupational settings. Organic solvents are widely employed in industry and are used in large quantities across the world. Occupational exposure to ...


Environmental monitoring and biomarkers of exposure to styrene in chemical indu...

Fernandes, Daniela; Meneses, Márcia; Albuquerque, Paula; Barros, Miguel

ABSTRACT - Biomarkers of exposure to chemicals, such as styrene, allows to estimate the exposure to a particular compound by measuring the compound or it(s) metabolite(s) in body fluids. As an example, the determination of mandelic acid and phenylglyoxylic acid in urine. Indicators of genotoxicity are categorized as: (a) DNA and protein adducts; (b) DNA strand breaks. Styrene metabolism is initiated by Cytochro...


Fungal contamination of sandpits from recreational parks and schools: a potenti...

Viegas, Carla; Brandão, João; Sabino, Raquel; Meneses, Márcia; Veríssimo, Carla

Sandpits used by children are frequently visited by wild life which constitutes a source of fungal pathogens and allergenic fungi. This study aimed to take an unannounced snapshot of the urban levels of fungal contaminants in sands, using for this purpose two public recreational parks, three elementary schools and two kindergartens. All samples were from Lisbon and neighboring municipalities and were tested for...


Analysis of surfaces for characterization of fungal burden: does it matter?

Viegas, Carla; Faria, Tiago; Meneses, Márcia; Carolino, Elisabete; Viegas, Susana; Gomes, Anita Quintal; Sabino, Raquel

Objectives: Mycological contamination of occupational environments can be a result of fungal spores’ dispersion in the air and on surfaces. Therefore, it is very important to assess it in both types of the samples. In the present study we assessed fungal contamination in the air and in the surface samples to show relevance of surfaces sampling in complementing the results obtained in the air samples. Material a...


Analysis of surfaces for characterization of fungal burden - Does it matter?

Viegas, Carla; Faria, Tiago; Meneses, Márcia; Carolino, Elisabete; Viegas, Susana; Gomes, Anita Quintal; Sabino, Raquel

Mycological contamination of occupational environments can be a result of fungal spores' dispersion in the air and on surfaces. Therefore, it is very important to assess it in both types of the samples. In the present study we assessed fungal contamination in the air and in the surface samples to show relevance of surfaces sampling in complementing the results obtained in the air samples.


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