Periodontitis is an inflammatory disease associated with bone loss and is a frequent cause of tooth loss in adults. Flavonoids are compounds abundant in vegetables and have anti- inflammatory actions. The aim of the present study was to investigate the role of flavonoids rutin and quercetin on the pathogenesis of experimental periodontal disease (EPD). EPD was induced in Wistar rats by placing a nylon thread ar...
Periodontitis, the major cause of teeth loss in adults, is an inflammatory disease in which occurs alveolar bone resorption and collagen fibers destruction. Bacteria and host factors are necessary to the development of this pathology. Bisphosphonates are a new class of drugs that inhibit bone resorbtion by causing morphological alterations or death of osteoclasts. The objetive of this study is to investigate th...
Periodontitis, a relevant cause of teeth loss in adults, is a chronic inflammatory disease characterized by alveolar bone resorption and collagen fibers and cementum destruction. S-nitrosogluthathione (GSNO) is considered to be an NO donor and to act as a reservoir of NO in vivo. The objective of this study was to investigate the effect of GSNO in experimental periodontal disease (EPD). EPD was induced by a nyl...