2 documents found, page 1 of 1
Cardiotoxicity in haematological diseases : are the tyrosine kinase inhibitors ...
Francisco, A. R. Gaspar Lopes; Alves, D.; Gonçalves, I. S.; Menezes, M. N.; Silva, G. Lima da; Guimarães, T.; David, C.; Braga, J.; Guerra, L.Introduction: Chemotherapy-induced cardiotoxicity is a growing concern. The true cardiotoxic impact of new drugs such as tyrosine kinase inhibitors is unknown, especially the ones used for chronic myeloid leukaemia. We aim to evaluate nilotinib and imatinib induced cardiotoxicity. Methods: Single-center prospective study of consecutive patients with chronic myeloid leukaemia treated with tyrosine kinase inhibit...
Prognostic significance of disrhythmias in patients with familiar amyloid polyn...
Francisco, A.R. Gaspar Lopes; Dias, N. Cortez; Menezes, M. N.; Guimarães, T.; Silva, G. Lima da; Plácido, R.; Magalhães, A.; Inácio, C.Background: Rhythm disturbances and conduction defects are common consequences of cardiac amyloid infiltration in familial amyloid polyneuropathy (FAP) V30M-TTR. The occurrence of dysrhythmias appears to increase with the severity of the disease but its prognostic value is still unknown. Purpose: To evaluate the occurrence of arrhythmias according to the patient's age and the duration of symptoms and to analyze...